{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:39:31Z","timestamp":1780533571631,"version":"3.54.1"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T00:00:00Z","timestamp":1599868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Prolonged ischemia of tissues inevitably leads to their necrosis. This is especially relevant in the case of transplantation or replantation. In such situations, reperfusion in a timely manner might not be possible due to transportation times or other unforeseen complications. Therefore, a readily available and simple method to oxygenate the tissue and thus widen the time frame to reperfusion seems desirable. Here, we present the case of extracorporal perfusion of a latissimus dorsi (LD) flap that was successfully transplanted after nearly 6\u2009hr of ischemia. A 41\u2010year\u2010old patient suffered multiple injuries including complete severance of the popliteal artery requiring emergency bypass. After stabilization of the patient and subsequent debridement, a LD flap was performed for soft tissue coverage. However, there was an acute occlusion of the bypass during flap inset. To salvage the free flap, a one\u2010way extracorporal perfusion of the flap with heparinized isotonic saline solution was performed for a total of 5 hr and 47\u2009min. The flap survived with minimal tip necrosis. This case report describes the application of a simple extracorporal perfusion technique for salvage of a free flap over a prolonged ischemia time and discusses the relevant literature. Due to its ease and quickness of application as well as ubiquitous availability, it might serve as a valuable tool in cases of acute problems with the recipient vessels or other incidents where several hours of ischemia time are to be anticipated.<\/jats:p>","DOI":"10.1002\/micr.30649","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T11:11:53Z","timestamp":1601032313000},"page":"75-78","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Transplantation of a latissimus dorsi flap after nearly 6 hr of extracorporal perfusion: A case report"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2822-421X","authenticated-orcid":false,"given":"Jonas","family":"Kolbenschlag","sequence":"first","affiliation":[{"name":"Department of Hand, Plastic, Reconstructive and Burn Surgery, BG Klinik T\u00fcbingen Eberhard Karls University Tuebingen  Tuebingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Lescan","sequence":"additional","affiliation":[{"name":"Department of Thoracic, Heart and Vascular Surgery Eberhard Karls University Tuebingen  Tuebingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Bahrs","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery, BG Klinik T\u00fcbingen Eberhard Karls University Tuebingen  Tuebingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antje","family":"Bornemann","sequence":"additional","affiliation":[{"name":"Department of Neuropathology Eberhard Karls University Tuebingen  Tuebingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrien","family":"Daigeler","sequence":"additional","affiliation":[{"name":"Department of Hand, Plastic, Reconstructive and Burn Surgery, BG Klinik T\u00fcbingen Eberhard Karls University Tuebingen  Tuebingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Department of Hand, Plastic, Reconstructive and Burn Surgery, BG Klinik T\u00fcbingen Eberhard Karls University Tuebingen  Tuebingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,12]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0967-2109(02)00070-4"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2016.09.010"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198609000-00003"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2007.11.032"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.30316"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002664"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0000000000000681"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.3233\/CH-162049"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.3233\/CH-170298"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003226"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.12238"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000000672"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2015.11.007"}],"container-title":["Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.30649","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/micr.30649","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/micr.30649","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T17:53:41Z","timestamp":1693677221000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/micr.30649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,12]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/micr.30649"],"URL":"https:\/\/doi.org\/10.1002\/micr.30649","archive":["Portico"],"relation":{},"ISSN":["0738-1085","1098-2752"],"issn-type":[{"value":"0738-1085","type":"print"},{"value":"1098-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,12]]},"assertion":[{"value":"2019-11-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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