{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:46:16Z","timestamp":1791902776013,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T00:00:00Z","timestamp":1615075200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Although two ways of reconstruction have been reviewed for a long period, comparison of large sample size with nearly randomized patient selection is rare. Here, we compare the surgical outcomes of these two methods from two large medical institutes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Totally 176 patients were included from two medical centers with different protocols, 62 patients from MacKay Hospital repair defects with fibula flaps using reconstruction plates. Also 114 patients from Kaohsiung ChangGung Hospital treat with reconstruction plates combine anterior lateral thigh flaps, in which 12 cases had secondary fibula flap after plate exposure. Electronic medical records were reviewed retrospectively. Short (3\u201312\u2009months) and long\u2010term (&gt;12\u2009months) outcomes were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Short\u2010term evaluation revealed that the secondary fibula had a higher rate of vascular complications (33 vs. 6%, <jats:italic>p<\/jats:italic> = .02). Primary fibula had a higher risk of post reconstructive surgical debridement (60 vs. 40%, <jats:italic>p<\/jats:italic> = .018). Long\u2010term follow\u2010up revealed radiation therapy significantly worsened bone healing (<jats:italic>p<\/jats:italic> = .03). Primary fibula had a lower rate of screw loosening (14.0 vs. 40.3%, <jats:italic>p<\/jats:italic> = .002). Radiation therapy did not increase the plate exposure rate among the groups (33 vs. 27%, <jats:italic>p<\/jats:italic> =\u2009.389). Disease free survival showed no significant difference between two groups (53.1 \u00b1\u20093.5 vs. 47.8 \u00b1\u20092.8 months, <jats:italic>p<\/jats:italic> = .317).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Primary fibula reconstruction should be considered whenever possible to reduce the risk of late complications and simplifies the management after a potential plate exposure. Notably, radiation therapy apparently has no significant effect on plate exposure rate both in ALT or fibula groups.<\/jats:p><\/jats:sec>","DOI":"10.1002\/micr.30729","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T06:30:45Z","timestamp":1615185045000},"page":"327-334","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Comparison of surgical outcomes between primary plate and fibular flap transfer for reconstruction of segmental mandibular defects"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0260-759X","authenticated-orcid":false,"given":"Tzu\u2010Huan","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery MacKay Memorial Hospital  Taipei 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