{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:15:08Z","timestamp":1757704508859,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,12,18]],"date-time":"2022-12-18T00:00:00Z","timestamp":1671321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The reconstruction of large fistulous defects following the radical ablation of maxillary sinus carcinoma remains challenging. The procedure requires not only the coverage of both intra\u2010nasal lining and cheek skin but also sufficient obliteration of dead space between the two surfaces. In this report, we present our experience on the reconstruction of through\u2010and\u2010through defects in the mid\u2010face with poly\u2010foliated chimeric perforator flaps.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nine patients (five males and four females) who received a two\u2010skin paddled and one muscle segment chimeric perforator flap reconstruction after maxillary sinus carcinoma ablation between March 2015 and December 2019 were retrospectively reviewed in authors' hospital. The mean age of the patients was 59.11. Six patients were diagnosed as squamous cell carcinoma, two as adenoid cystic carcinoma, and one as adenocarcinoma. Brown class IIIa defects were found in eight patients, and one patient had a Brown class IVa defect. The mean size of intra\u2010nasal defect was 5.67\u2009\u00d7\u20094.06\u2009cm<jats:sup>2<\/jats:sup>, and the mean size of facial skin defect was 8.94\u2009\u00d7\u20096.56\u2009cm<jats:sup>2<\/jats:sup>. ALT flaps were used in five patients, LD flaps in four patients. The minor skin paddle was firstly inset to the mucosal defect site as the lining. Then, the muscle segment was inset to eliminate the dead cavity. Finally, the major skin paddle was inset to recover the cutaneous defect.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In ALT group, the mean size of the minor skin paddle was 5.7\u2009\u00d7\u20094.7\u00a0cm<jats:sup>2<\/jats:sup>, and the mean size of the major skin paddle was 8.7\u2009\u00d7\u20096.6\u00a0cm<jats:sup>2<\/jats:sup>. In LD group, the mean size of the minor skin paddle was 6.88\u2009\u00d7\u20094.38\u2009cm<jats:sup>2<\/jats:sup>, and the mean size of the major skin paddle was 11\u2009\u00d7\u20097.75\u2009cm<jats:sup>2<\/jats:sup>.All donor sites were closed primarily. All flaps survived and no partial flap loss was encountered. The mean follow\u2010up time was 14.67\u2009months, and there were no major postoperative complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of poly\u2010foliated chimeric perforator free flaps can provide functional and aesthetic coverage for extensive through\u2010and\u2010through mid\u2010face defects without significant donor\u2010site morbidities.<\/jats:p><\/jats:sec>","DOI":"10.1002\/micr.30996","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T07:30:58Z","timestamp":1671435058000},"page":"476-482","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["One stage reconstruction of mid\u2010face fistulous defects after maxillary sinus carcinoma resection with chimeric perforator free flaps"],"prefix":"10.1002","volume":"43","author":[{"given":"Yudi","family":"Han","sequence":"first","affiliation":[{"name":"Department of Plastic and 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