{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T19:37:42Z","timestamp":1782589062899,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T00:00:00Z","timestamp":1671580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A radical parotidectomy with facial nerve sacrifice results in facial nerve paralysis as well as a volume and often cutaneous defect. Prior experience with nerve grafting and static suspension has yielded suboptimal results. The present report aims to examine the feasibility and outcomes of a combined free gracilis and profunda artery perforator (PAP) flap from a single donor site can reconstruct these extensive defects and potentially restore dynamic facial reanimation even in the setting of adjuvant radiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>A retrospective review of 10 patients (6 males and 4 females) was performed from 2016 to 2020 that underwent a combined PAP\u2010gracilis reconstruction of a radical parotidectomy defect. All patients (mean age: 71.3\u2009years; range: 52\u201383\u2009years) received adjuvant radiation. A chimeric PAP\u2010gracilis flap requiring a single microvascular anastomosis was performed in three patients while the remaining patients underwent a double free flap reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The gracilis flap was innervated using the facial nerve stump, spinal accessory and massecteric nerve in three patients each. One patient's gracilis was innervated using the hypoglossal nerve. Three patients also underwent nerve grafting of the facial nerve. One patient was taken back to the operating room for a hematoma in the recipient site and there were not flap losses of either the PAP or gracilis flap. Two patients had delayed wound healing of the donor site that healed with conservative management. Average follow\u2010up was 11.1\u00a0months (range: 8.1\u201319.5\u00a0months). Six patients were able to achieve dynamic animation while the others obtained a static reconstruction and did not have issues with drooling, eating, or speaking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Immediate functional muscle transfer can potentially restore dynamic facial reanimation even following radiation. Combining reconstruction using a PAP\u2010gracilis flap addresses the soft tissue deficit and facial paralysis using a single donor site in a single operation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/micr.30997","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T10:27:58Z","timestamp":1671618478000},"page":"309-315","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The combined profunda artery perforator\u2010gracilis flap for immediate facial reanimation and resurfacing of the radical parotidectomy defect"],"prefix":"10.1002","volume":"43","author":[{"given":"Christopher M. K.","family":"Yao","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yelda","family":"Jozaghi","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery University of Texas MD Anderson Cancer Center  Houston Texas USA"},{"name":"Department of Head and Neck Surgery University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Danker","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7665-6802","authenticated-orcid":false,"given":"Reem","family":"Karami","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery University of Texas 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul W.","family":"Gidley","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1067-9750","authenticated-orcid":false,"given":"Edward I.","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery University of Texas MD Anderson Cancer Center  Houston Texas 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