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In recent years, dramatic advances in technology and collaborations between different specialties (such as orthopedic, oncology, radiology, plastic, and vascular surgery) significantly changed the approach to complex malignant tumors without resorting to limb removal. The combination of the strengths of both orthopedic surgery and plastic surgery constitutes the modern definition of \u201corthoplasty.\u201d The aim of this review article is to provide treatment strategies that are available for reconstruction of foot and ankle in limb\u2010salvage surgery after tumor resection, with a specific focus on microsurgical techniques in plastic surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a comprehensive search for relevant papers across PubMed, Scopus, Embase, and Web of Science. We included patient\u2010based studies reporting on procedures for soft\u2010tissue reconstruction with small and large soft tissue defects. Indications, pros and cons, and technique tips are discussed for each type of reconstructive technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The search was done using literature of the past 30\u2009years (from 1990 to date), resulting in about 725 articles describing over 2000 cases. Cutaneous flaps included lateral supramalleolar flap, medial plantar flap, reverse sural neurocutaneous island flap, medial leg flap, and lateral leg flap. Free flaps included anterolateral thigh flap, radial forearm flap, latissimus dorsi flap, gracilis muscle flap, lateral arm flap, and rectus abdominis flap.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The orthoplastic approach in musculoskeletal oncology is a collaborative model of orthopedic and plastic surgeons working together, resulting in a higher rate of successful limb salvage in patients at risk for amputation. Protocols, biologic substitutes, and surgical techniques are largely improved in the last decades increasing the possibility of functional reconstruction. Microsurgical strategies represent the new frontiers in these demanding reconstructions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/micr.31168","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T06:39:07Z","timestamp":1711694347000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Ortho\u2010oncoplastic surgery in foot and ankle: A narrative overview on reconstruction of soft\u2010tissue defects after oncologic resections"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8823-448X","authenticated-orcid":false,"given":"Andrea","family":"Angelini","sequence":"first","affiliation":[{"name":"Department of Orthopedics and Orthopedic Oncology University of Padua  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Tiengo","sequence":"additional","affiliation":[{"name":"Department of Plastic surgery University of 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