{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T13:45:32Z","timestamp":1764423932355,"version":"3.46.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T00:00:00Z","timestamp":1740355200000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microsurgery"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Vascularized periosteal transplants have proven to be highly effective and rapid in promoting bone healing in biologically complex nonunions in children, with several reported donor sites. This study aimed to assess the feasibility of harvesting a vascularized diaphyseal femoral periosteal flap (VDFPF) from cadavers and evaluate its clinical application in two cases of bilateral congenital pseudarthrosis of the tibia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study investigated the periosteal branches of the deep femoral vessels (DFV) supplying the femoral diaphysis in 19 previously latex\u2010injected cadavers. The femur was divided into four segments. The distance from the midpoint of the inguinal ligament to the origin of the DFV and the number of periosteal branches were recorded. The vascularized diaphyseal femoral periosteal flap (VDFPF) was used to treat one side in two patients with bilateral congenital pseudarthrosis of the tibia (aged 14 and 2\u2009years).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The DFV's origin was located at a mean of 4.2\u2009cm (range 2.8\u20138.5\u2009cm) distal to the midpoint of the inguinal ligament. In 15 cases, the DFV coursed adjacent to the second and third quarters of the femoral shaft, providing a mean number of 5 (range 4\u20138) periosteal branches, allowing for the harvesting of a new pure vascularized periosteal flap. Healing of congenital pseudarthrosis of the tibia occurred within 3\u2009months in both patients, with no donor or recipient site complications at the final follow\u2010up of 13\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The VDFPF may be an effective periosteal transplant and a viable alternative to other large free periosteal transplants used in children for treating complex non\u2010unions, especially when tibial and fibular donors are not available. Bone union was fast compared to other techniques used to treat these challenging cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/micr.70043","type":"journal-article","created":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T04:22:53Z","timestamp":1740543773000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vascularized Deep Femoral Periosteal Flap: Anatomical Study and Clinical Application in Congenital Pseudarthrosis of the Tibia in Two Cases"],"prefix":"10.1002","volume":"45","author":[{"given":"Antonio Carlos","family":"da Costa","sequence":"first","affiliation":[{"name":"Orthopaedic and Traumatology Surgery Department Santa Casa de Sao Paulo, Hand Surgery and Microsurgery Group  Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Romero\u2010Larrauri","sequence":"additional","affiliation":[{"name":"Pediatric Orthopaedic Surgery San Juan de Dios Clinic  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana","family":"Rojas\u2010Neira","sequence":"additional","affiliation":[{"name":"Hand Surgery and Microsurgery Department Farallones Clinic, Christus Health  Cali Colombia"},{"name":"Pontificia Javeriana University  Cali Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1635-8774","authenticated-orcid":false,"given":"Diego","family":"Gonzalez\u2010Morgado","sequence":"additional","affiliation":[{"name":"Orthopaedic Surgery Department Hospital Universitari Vall d'Hebron, Universitat Autonoma de Barcelona  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amr","family":"Fouad","sequence":"additional","affiliation":[{"name":"Hand Surgery Department Shifa Hospital, Al\u2010Azhar University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Alves","sequence":"additional","affiliation":[{"name":"Department of Pediatric Orthopaedics Hospital Pedi\u00e1trico de Coimbra\u2014CHUC, EPE  Coimbra Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Soldado","sequence":"additional","affiliation":[{"name":"Pediatric Hand Surgery and Microsurgery Unit Instituto de Investigaci\u00f3n Sanitaria HM Hospitales  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,24]]},"reference":[{"issue":"5","key":"e_1_2_7_2_1","first-page":"1499","article-title":"Bilateral Congenital Pseudarthrosis of the Tibia With Neurofibromatosis Type 1","volume":"71","author":"Ari B.","year":"2021","journal-title":"Journal of the Pakistan Medical 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