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This includes the study of chemical space coverage, physicochemical properties and Bemis\u2010Murcko (BM) scaffold populations. More than 5\u2005K CN\u2010unique scaffolds (relative to ZINC and ChEMBL collections) were identified. Generative Topographic Maps (GTMs) accommodating those libraries were generated and used to compare the compound populations. Hierarchical GTM (\u00abzooming\u00bb) was applied to generate an ensemble of maps at various resolution levels, from global overview to precise mapping of individual structures. The respective maps were added to the ChemSpace Atlas website. 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