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The orange juice contained 168 \u03bcmol of hesperetin\u20107\u2010<jats:italic>O<\/jats:italic>\u2010rutinoside and 18 \u03bcmol of naringenin\u20107\u2010<jats:italic>O<\/jats:italic>\u2010rutinoside. GC\u2010MS analysis of the urine identified nine phenolic acids, five of which, 3\u2010hydroxyphenylacetic acid, 3\u2010hydroxyphenylhydracrylic acid, dihydroferulic acid, 3\u2010methoxy\u20104\u2010hydroxyphenylhydracrylic acid and 3\u2010hydroxyhippuric acid, were associated with orange juice consumption indicating that they were derived from colonic catabolism of hesperetin\u20107\u2010<jats:italic>O<\/jats:italic>\u2010rutinoside. The overall 0\u201324 h excretion of the five phenolic acids was 6.7 \u00b1 1.8 \u03bcmol after drinking water and this increased significantly (<jats:italic>p<\/jats:italic> &lt; 0.05) to 62 \u00b1 18 \u03bcmol, equivalent to 37% of the ingested flavanones, following orange juice consumption. When the orange juice was ingested with yoghurt excretion fell back markedly to 9.3 \u00b1 4.4 \u03bcmol. This was not due to a difference in mouth to caecum transit time, as measured with breath hydrogen production, though possibly there may have been a slowing of the bulk of the meal reaching the large intestine which may then have altered the catabolism of the flavanones to phenolic acids by the colonic microbiota.<\/jats:p>","DOI":"10.1002\/mnfr.200800287","type":"journal-article","created":{"date-parts":[[2009,5,4]],"date-time":"2009-05-04T13:18:47Z","timestamp":1241443127000},"source":"Crossref","is-referenced-by-count":90,"title":["Yoghurt impacts on the excretion of phenolic acids derived from colonic breakdown of orange juice flavanones in humans"],"prefix":"10.1002","volume":"53","author":[{"given":"Suri","family":"Roowi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Mullen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine A.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Crozier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,5,27]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","unstructured":"Crozier A. 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