{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:40:49Z","timestamp":1788871249745,"version":"build-2803163510"},"reference-count":64,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,5,19]],"date-time":"2011-05-19T00:00:00Z","timestamp":1305763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"California Breast Cancer Research Program and the WHH Foundation","award":["R01CA144034"],"award-info":[{"award-number":["R01CA144034"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Nutrition Food Res"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Scope<\/jats:bold>\n                    : Observational studies have evaluated the relationship between green tea intake and cancers of the ovary and endometrium, but we are not aware of the published studies on green tea intake and risk of human papillomavirus (HPV)\u2010related cancers of the cervix, vagina, or vulva.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods and results<\/jats:bold>\n                    : A critical review of the published literature on tea intake and risk of ovarian and endometrial cancers was conducted. In meta\u2010analyses, we report inverse associations for green tea intake and risk of ovarian cancer (odds ratio [OR]=0.66; 95% confidence interval [CI]: 0.54, 0.80), and for green tea and risk of endometrial cancer (OR=0.78, 95% CI: 0.62, 0.98). There was no association for black tea and ovarian cancer risk (OR=0.94, 95% CI: 0.87, 1.02) and a positive association with endometrial cancer risk (OR=1.20, 95% CI: 1.05, 1.38). We summarized the experimental evidence supporting the antiviral and immunomodulatory activities of green tea catechins, and results from randomized clinical trials that demonstrated green tea catechin efficacy on treatment of cervical lesions and external genital warts.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion<\/jats:bold>\n                    : Observational data support a protective role of green tea on risk of ovarian and endometrial cancers. Observational data are needed to evaluate whether green tea reduces risk of human papillomavirus\u2010related cancers.\n                  <\/jats:p>","DOI":"10.1002\/mnfr.201100058","type":"journal-article","created":{"date-parts":[[2011,5,19]],"date-time":"2011-05-19T05:23:23Z","timestamp":1305782603000},"page":"931-940","source":"Crossref","is-referenced-by-count":53,"title":["Green and black tea in relation to gynecologic cancers"],"prefix":"10.1002","volume":"55","author":[{"given":"Lesley M.","family":"Butler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna H.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,19]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.55.2.74"},{"key":"e_1_2_8_3_2","unstructured":"World Cancer Research Fund\/American Institute for Cancer Research. Food Nutrition Physical Activity and the Prevention of Cancer: a Global Perspective AICR Washington DC2007."},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S4517"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31819bd6e0"},{"key":"e_1_2_8_6_2","first-page":"1123","article-title":"Antitumor effect of green tea polyphenol epigallocatechin\u20103\u2010gallate in ovarian carcinoma cells: evidence for the endothelin\u20101 as a potential target","volume":"231","author":"Spinella F.","year":"2006","journal-title":"Exp. Biol. Med."},{"key":"e_1_2_8_7_2","first-page":"413","article-title":"Combination of theanine with doxorubicin inhibits hepatic metastasis of M5076 ovarian sarcoma","volume":"5","author":"Sugiyama T.","year":"1999","journal-title":"Clin. Cancer Res."},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/den245"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/den417"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-2638"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/IGC.0b013e3181c7ca5c"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.200500142"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604008"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.05.027"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-010-9577-7"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.07.030"},{"key":"e_1_2_8_17_2","first-page":"323","article-title":"[Green tea consumption and the risk of endometrial cancer: a population\u2010based case\u2010control study in urban Shanghai]","volume":"26","author":"Gao J.","year":"2005","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1207\/S15327914NC4601_03"},{"key":"e_1_2_8_19_2","first-page":"713","article-title":"Tea consumption and ovarian cancer risk: a case\u2010control study in China","volume":"11","author":"Zhang M.","year":"2002","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-07-2511"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.20456"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23760"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2007.00391.x"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-008-9272-0"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1080\/01635580802192833"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm242"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-010-9575-9"},{"key":"e_1_2_8_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/88.16.1127"},{"key":"e_1_2_8_29_2","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1500161"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djh167"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-1417"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a008905"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.24125"},{"key":"e_1_2_8_34_2","doi-asserted-by":"publisher","DOI":"10.1177\/107327480000700312"},{"key":"e_1_2_8_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930601)71:11<3575::AID-CNCR2820711119>3.0.CO;2-0"},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1080\/01635589209514170"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1866"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.07.064"},{"key":"e_1_2_8_39_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008469-200310000-00007"},{"key":"e_1_2_8_40_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02441.x"},{"key":"e_1_2_8_41_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08520.x"},{"key":"e_1_2_8_42_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181719b60"},{"key":"e_1_2_8_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1702(02)00190-9"},{"key":"e_1_2_8_44_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-009-1917-3"},{"key":"e_1_2_8_45_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-009-9240-x"},{"key":"e_1_2_8_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2003.09.023"},{"key":"e_1_2_8_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mt.6300221"},{"key":"e_1_2_8_48_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/128.12.2334"},{"key":"e_1_2_8_49_2","doi-asserted-by":"publisher","DOI":"10.1124\/mol.52.3.465"},{"key":"e_1_2_8_50_2","doi-asserted-by":"publisher","DOI":"10.1080\/10408390802145310"},{"key":"e_1_2_8_51_2","doi-asserted-by":"publisher","DOI":"10.2174\/156800907781386605"},{"key":"e_1_2_8_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601084"},{"key":"e_1_2_8_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2004.09.024"},{"key":"e_1_2_8_54_2","doi-asserted-by":"publisher","DOI":"10.3177\/jnsv.51.335"},{"key":"e_1_2_8_55_2","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2007.10719634"},{"key":"e_1_2_8_56_2","doi-asserted-by":"publisher","DOI":"10.1080\/01635580701307945"},{"key":"e_1_2_8_57_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22790"},{"key":"e_1_2_8_58_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2006.00773.x"},{"key":"e_1_2_8_59_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.22.2683"},{"key":"e_1_2_8_60_2","doi-asserted-by":"publisher","DOI":"10.1023\/B:CACO.0000027482.00077.8b"},{"key":"e_1_2_8_61_2","doi-asserted-by":"publisher","DOI":"10.1207\/S15327914nc391_4"},{"key":"e_1_2_8_62_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0215(20001015)88:2<313::AID-IJC26>3.0.CO;2-5"},{"key":"e_1_2_8_63_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/16.1.13"},{"key":"e_1_2_8_64_2","first-page":"681","article-title":"A case\u2010control study of dietary and nondietary factors in ovarian cancer","volume":"71","author":"Byers T.","year":"1983","journal-title":"J. Natl. Cancer Inst."},{"key":"e_1_2_8_65_2","first-page":"5077","article-title":"Diet, body size, physical activity, and the risk of endometrial cancer","volume":"57","author":"Goodman M. T.","year":"1997","journal-title":"Cancer Res."}],"container-title":["Molecular Nutrition &amp; Food Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmnfr.201100058","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmnfr.201100058","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mnfr.201100058","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T03:44:40Z","timestamp":1694490280000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201100058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,19]]},"references-count":64,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["10.1002\/mnfr.201100058"],"URL":"https:\/\/doi.org\/10.1002\/mnfr.201100058","archive":["Portico"],"relation":{},"ISSN":["1613-4125","1613-4133"],"issn-type":[{"value":"1613-4125","type":"print"},{"value":"1613-4133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,19]]}}}