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Epigenomic marks are heritable but are also responsive to environmental shifts, such as changes in nutritional status, and are especially vulnerable during development. <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content><\/jats:italic>\u2010adenosylmethionine is the methyl group donor for <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> methylation and several nutrients are required for the production of <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content><\/jats:italic>\u2010adenosylmethionine. These methyl nutrients include vitamins (folate, riboflavin, vitamin B12, vitamin B6, choline) and amino acids (methionine, cysteine, serine, glycine). As such, imbalances in the metabolism of these nutrients have the potential to affect DNA methylation. 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