{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T23:38:44Z","timestamp":1787701124611,"version":"build-2784847793"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,11,14]],"date-time":"2014-11-14T00:00:00Z","timestamp":1415923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Nutrition Food Res"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:p>White rice (WR) is a major staple food for people in developing countries and it may be responsible for the growing incidence of type 2 diabetes. Nonpregnant Female Sprague Dawley rats fed with WR or brown rice (BR) for 8 weeks were mated with age\u2010matched male rats maintained on normal pellet over the same period. Offsprings were fed normal pellet after weaning until 8 weeks postdelivery. Rats fed with WR and their offsprings showed worsened oral glucose tolerance test, lower serum adiponectin levels, and higher weights, homeostatic model assessment of insulin resistance, serum retinol binding protein\u20104 levels, and leptin levels, compared with the normal and BR groups, suggesting an increased risk of insulin resistance. Furthermore, transcriptional levels of genes involved in insulin signaling showed different expression patterns in the liver, muscle, and adipose tissues of mothers and offsprings in both WR and BR groups. The results propose that the cycle of WR\u2010induced insulin resistance in offsprings due to prenatal exposure, followed by their consumption of WR later in life may contribute to diabetes incidents. These findings are worth studying further.<\/jats:p>","DOI":"10.1002\/mnfr.201400396","type":"journal-article","created":{"date-parts":[[2014,10,20]],"date-time":"2014-10-20T09:53:35Z","timestamp":1413798815000},"page":"180-184","source":"Crossref","is-referenced-by-count":8,"title":["Increased risk of insulin resistance in rat offsprings exposed prenatally to white rice"],"prefix":"10.1002","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9888-4809","authenticated-orcid":false,"given":"Mustapha Umar","family":"Imam","sequence":"first","affiliation":[{"name":"Laboratory of Molecular Biomedicine Institute of Bioscience Universiti Putra Malaysia  Serdang Selangor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maznah","family":"Ismail","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biomedicine Institute of Bioscience Universiti Putra Malaysia  Serdang Selangor Malaysia"},{"name":"Department of Nutrition and Dietetics Faculty of Medicine and Health Sciences Universiti Putra Malaysia  Serdang Selangor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Der\u2010Jiun","family":"Ooi","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biomedicine Institute of Bioscience Universiti Putra Malaysia  Serdang Selangor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadarajan","family":"Sarega","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biomedicine Institute of Bioscience Universiti Putra Malaysia  Serdang Selangor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aminu","family":"Ishaka","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biomedicine Institute of Bioscience Universiti Putra Malaysia  Serdang Selangor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,14]]},"reference":[{"key":"e_1_2_4_2_1","unstructured":"International Diabetes Federation.Diabetes Atlas: 2013. Available athttp:\/\/www.idf.org\/diabetesatlas. Accessed April 2014."},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-0442"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.109"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e1454"},{"key":"e_1_2_4_6_1","volume-title":"Marketing of value\u2010added rice products in Japan: germinated brown rice and rice bread","author":"Ito S.","year":"2004"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/db09-1003"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2014.03.013"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.90207.2008"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2012.12.007"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature03711"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.2337\/db08-1470"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/127.6.1077"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI23108"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1185"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI3326"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.051011"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.47.3.387"},{"key":"e_1_2_4_19_1","doi-asserted-by":"crossref","first-page":"14393","DOI":"10.1016\/S0021-9258(17)38731-8","article-title":"Transcriptional and post\u2010transcriptional regulation of L\u2010type pyruvate kinase in diabetic rat liver by insulin and dietary fructose","volume":"260","author":"Noguchi T.","year":"1985","journal-title":"J. Biol. Chem."},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1677\/JOE-07-0097"},{"key":"e_1_2_4_21_1","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1080\/00325481.1958.11692236","article-title":"Effects of rice diet on diabetes mellitus associated with vascular disease","volume":"24","author":"Kempner W.","year":"1958","journal-title":"Postgrad. Med."},{"key":"e_1_2_4_22_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.6.2.197"},{"key":"e_1_2_4_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e3094"},{"key":"e_1_2_4_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e2021"},{"key":"e_1_2_4_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e3099"},{"key":"e_1_2_4_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201200429"},{"key":"e_1_2_4_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/10942912.2012.717153"},{"key":"e_1_2_4_28_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-0556"}],"container-title":["Molecular Nutrition &amp; Food Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmnfr.201400396","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mnfr.201400396","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T22:04:58Z","timestamp":1694469898000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201400396"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,14]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1002\/mnfr.201400396"],"URL":"https:\/\/doi.org\/10.1002\/mnfr.201400396","archive":["Portico"],"relation":{},"ISSN":["1613-4125","1613-4133"],"issn-type":[{"value":"1613-4125","type":"print"},{"value":"1613-4133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,14]]}}}