{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:39:50Z","timestamp":1793039990556,"version":"4.5.0"},"reference-count":70,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,2,16]],"date-time":"2020-02-16T00:00:00Z","timestamp":1581811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81671978"],"award-info":[{"award-number":["81671978"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81471991"],"award-info":[{"award-number":["81471991"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81772143"],"award-info":[{"award-number":["81772143"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81700463"],"award-info":[{"award-number":["81700463"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81374101"],"award-info":[{"award-number":["81374101"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Nutrition Food Res"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec>\n                    <jats:title>Scope<\/jats:title>\n                    <jats:p>A high\u2010salt diet is a cause of gastritis, but the associated mechanism remains unclear. Recent studies have shown that gastric flora is associated with a variety of stomach diseases, but it is not known whether gastric flora is involved in gastritis induced by a high\u2010salt diet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Gastritis is successfully induced in C57BL\/6 mice fed a high\u2010salt diet (salt: 5% NaCl) for four weeks. Through 16S rRNA gene sequencing, the composition of the stomach microbiota of mice fed normal and high\u2010salt diets are compared, the results of which show that the high\u2010salt diet induces significant changes in the gastric flora. Phylogenetic investigation of communities by reconstruction of unobserved states (PICRUSt) is used to predict the function of the microbiota in the stomach of mice, and the results indicate that a high\u2010salt diet leads to a decrease in the ability of the gastric microbiota to metabolize polysaccharides and vitamins. A buckwheat diet is used to treat gastritis. The results show gastritis induced by the high\u2010salt diet is significantly alleviated, and the dysbiosis in the stomach also improved.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Buckwheat diet may be one of the ways to prevent and treat gastritis caused by a high\u2010salt diet.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mnfr.201900965","type":"journal-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T17:03:41Z","timestamp":1581095021000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["High\u2010Salt Diet\u2010Induced Gastritis in C57BL\/6 Mice is Associated with Microbial Dysbiosis and Alleviated by a Buckwheat Diet"],"prefix":"10.1002","volume":"64","author":[{"given":"Ya","family":"Li","sequence":"first","affiliation":[{"name":"Department of Microbiology Key Laboratory for Experimental Teratology of Ministry of Education Key Laboratory of Infection and Immunology of Shandong Province, School of Basic Medicine Shandong University  Jinan 250012 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Microbiology Key Laboratory for Experimental Teratology of Ministry of Education Key Laboratory of Infection and Immunology of Shandong Province, School of Basic Medicine Shandong University  Jinan 250012 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Basic Medicine  Shandong University  Jinan 250012 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Drum Tower Hospital Medical School of Nanjing University  Nanjing 210093 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junze","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Microbiology Key Laboratory for Experimental Teratology of Ministry of Education Key Laboratory of Infection and Immunology of Shandong Province, School of Basic Medicine Shandong University  Jinan 250012 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[{"name":"School of Control Science and Engineering Shandong University  Jinan 250061 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjuan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Microbiology Key Laboratory for Experimental Teratology of Ministry of Education Key Laboratory of Infection and Immunology of Shandong Province, School of Basic Medicine Shandong University  Jinan 250012 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5260-2212","authenticated-orcid":false,"given":"Yundong","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Microbiology Key Laboratory for Experimental Teratology of Ministry of Education Key Laboratory of Infection and Immunology of Shandong Province, School of Basic Medicine Shandong University  Jinan 250012 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,16]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2015.1019918"},{"key":"e_1_2_8_2_1","first-page":"8","volume":"386","author":"Burden G.","year":"2015","journal-title":"Lancet"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23262"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.372"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2008.02.026"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-309252"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-16-1024"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02970315"},{"key":"e_1_2_8_9_1","first-page":"6735","volume":"52","author":"Correa P","year":"1992","journal-title":"Cancer Res."},{"key":"e_1_2_8_10_1","unstructured":"World Health Organization Guideline: Sodium Intake for Adults and Children WHO Geneva2014."},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1304127"},{"key":"e_1_2_8_12_1","first-page":"3518","volume":"48","author":"Henderson B.","year":"1988","journal-title":"Cancer Res."},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2005.00006.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.01.035"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000481627"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3402\/mehd.v26.26191"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2017-314205"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep04202"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i17.4948"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050640614566846"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2012.10.020"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884533610368714"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114508094658"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.427"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-018-0433-4"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature24628"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114507793923"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2012.00941.x"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-017-1175-y"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11319"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu5010234"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni0111-5"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2014.11.007"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11868"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11984"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature24628"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.02080"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2016.03.010"},{"key":"e_1_2_8_39_1","first-page":"10","volume":"3","author":"Przybylski R.","year":"2009","journal-title":"Eur. J. Plant Sci. Biotechnol."},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.5b02498"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw139"},{"key":"e_1_2_8_42_1","first-page":"4823","volume":"59","author":"Fox J. G.","year":"1999","journal-title":"Cancer Res."},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2012.11.013"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.2406"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0506655103"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2012.133"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000194"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI30111"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-016-0181-2"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201700184"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-017-1523-y"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2015.10.014"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-018-1810-2"},{"key":"e_1_2_8_54_1","first-page":"e00470","volume":"8","author":"Kang C.","year":"2017","journal-title":"mBio"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2019.03.023"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu9121329"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evu050"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1264\/jsme2.ME14054"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2015.11.018"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757-4749-5-23"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2005.04.008"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.7.3504-3511.1999"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000662"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38967"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2013.155"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/bfgp\/elt014"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005963107"},{"key":"e_1_2_8_68_1","first-page":"54","volume":"4","author":"Wronkowska M.","year":"2010","journal-title":"Eur. J. Plant Sci. Biotechnol."},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1080\/19390211.2017.1305477"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46660-0"}],"container-title":["Molecular Nutrition &amp; Food Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmnfr.201900965","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mnfr.201900965","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mnfr.201900965","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mnfr.201900965","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T02:10:14Z","timestamp":1694052614000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201900965"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,16]]},"references-count":70,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1002\/mnfr.201900965"],"URL":"https:\/\/doi.org\/10.1002\/mnfr.201900965","archive":["Portico"],"relation":{},"ISSN":["1613-4125","1613-4133"],"issn-type":[{"value":"1613-4125","type":"print"},{"value":"1613-4133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,16]]},"assertion":[{"value":"2019-09-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1900965"}}