{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:02:40Z","timestamp":1753869760935,"version":"3.41.2"},"reference-count":46,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,6,8]],"date-time":"2024-06-08T00:00:00Z","timestamp":1717804800000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010781","name":"Diabetes-Stiftung","doi-asserted-by":"publisher","award":["FP\u20100454\u20102023"],"award-info":[{"award-number":["FP\u20100454\u20102023"]}],"id":[{"id":"10.13039\/100010781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01EA1709"],"award-info":[{"award-number":["01EA1709"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Nutrition Food Res"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec><jats:title>Scope<\/jats:title><jats:p>Interindividual variations in postprandial metabolism and weight loss outcomes have been reported. The literature suggests links between postprandial metabolism and weight regulation. Therefore, the study aims to evaluate if postprandial glucose metabolism after a glucose load predicts anthropometric outcomes of a weight loss intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Anthropometric data from adults with obesity (18\u201365 years, body mass index [BMI] 30.0\u201339.9\u00a0kg\u00a0m<jats:sup>\u22122<\/jats:sup>) are collected pre\u2010 and post an 8\u2010week formula\u2010based weight loss intervention. An oral glucose tolerance test (OGTT) is performed at baseline, from which postprandial parameters are derived from glucose and insulin concentrations. Linear regression models explored associations between these parameters and anthropometric changes (\u2206) postintervention. A random forest model is applied to identify predictive parameters for anthropometric outcomes after intervention. Postprandial parameters after an OGTT of 158 participants (63.3% women, age 45 \u00b1 12, BMI 34.9 \u00b1 2.9\u00a0kg\u00a0m<jats:sup>\u22122<\/jats:sup>) reveal nonsignificant associations with changes in anthropometric parameters after weight loss (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a00.05). Baseline fat\u2010free mass (FFM) and sex are primary predictors for \u2206 FFM [kg].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Postprandial glucose metabolism after a glucose load does not predict anthropometric outcomes after short\u2010term weight loss via a formula\u2010based low\u2010calorie diet in adults with obesity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mnfr.202400106","type":"journal-article","created":{"date-parts":[[2024,6,8]],"date-time":"2024-06-08T11:00:12Z","timestamp":1717844412000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between the Postprandial Response to an Oral Glucose Tolerance Test and Anthropometric Changes After an 8\u2010Week Low\u2010Calorie Formula Diet \u2013 Results From the Lifestyle Intervention (LION) Study"],"prefix":"10.1002","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1752-2994","authenticated-orcid":false,"given":"Anna","family":"Reik","sequence":"first","affiliation":[{"name":"Institute for Nutritional Medicine, School of Medicine and Health Technical University of Munich  80992 Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunther","family":"Schauberger","sequence":"additional","affiliation":[{"name":"Chair of Epidemiology, School of Medicine and Health Technical University of Munich  80992 Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meike","family":"Wiechert","sequence":"additional","affiliation":[{"name":"Institute for Nutritional Medicine, School of Medicine and Health Technical University of Munich  80992 Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"Hauner","sequence":"additional","affiliation":[{"name":"Institute for Nutritional 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