{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:41:15Z","timestamp":1787506875728,"version":"build-2736575974"},"reference-count":201,"publisher":"Wiley","issue":"24","license":[{"start":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:00:00Z","timestamp":1733270400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Nutrition Food Res"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Alzheimer's disease (AD), a progressiveneurodegenerative condition is marked by extensive damage in the brain and dementia. Among the pathological hallmarks of AD is beta\u2010amyloid (A\u03b2). Production of toxic A\u03b2 oligomers production and accumulation in the brain is among the characteristic features of the disease. The abnormal accumulation A\u03b2 is initiated by the catalytic degradation of Amyloid Precursor Proteins (APP) by Beta Amyloid Cleaving Enzyme 1 (BACE1) to generate insoluble amyloid plaques. The abnormal proteins are mitochondrial poison which disrupt the energy production and liberate excessive free radicals causing neuronal damage and mutations. Consequently, targeting A\u03b2\u2010associated pathways has become a focus in the pursuit of developing effective AD treatments. An obstacle faced by many medications used to treat neurodegenerative diseases (NDs) is the restricted permeability across the blood\u2010brain barrier (BBB). Unfortunately, no anti\u2010amyloid drug is clinically approved till now. Recent advancements in nanotechnology have provided a possible solution for delivering medications to specific targets. By integrating natural products with nano\u2010medicinal approaches, it is possible to develop novel and highly efficient therapeutic strategies for the treatment of AD.<\/jats:p>","DOI":"10.1002\/mnfr.202400525","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T03:41:18Z","timestamp":1733283678000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Polyphenols and Their Biogenic Nano\u2010Formulations Targeting BACE1 as Anti\u2010Amyloid Therapies; Meeting the Challenges of Bioavailability, Safety, and Specificity for the Treatment of Alzheimer's Disease"],"prefix":"10.1002","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6060-5533","authenticated-orcid":false,"given":"Mohammed Ahmed","family":"Elawad","sequence":"first","affiliation":[{"name":"Public health Department Health Sciences College at Lieth Umm Al Qura University  Makkah 21955 Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4299-2445","authenticated-orcid":false,"given":"Muhammad","family":"Ayaz","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Faculty of Biological Sciences University of Malakand  18800 Dir (L) Chakdara KP Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5052-7116","authenticated-orcid":false,"given":"Osama F.","family":"Mosa","sequence":"additional","affiliation":[{"name":"Public health Department Health Sciences College at Lieth Umm Al Qura University  Makkah 21955 Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assad","family":"Usman","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Faculty of Biological Sciences University of Malakand  18800 Dir (L) Chakdara KP Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9068-3818","authenticated-orcid":false,"given":"Alashary Adam Eisa","family":"Hamdoon","sequence":"additional","affiliation":[{"name":"Public health Department Health Sciences College at Lieth Umm Al Qura University  Makkah 21955 Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8999-3464","authenticated-orcid":false,"given":"Saud","family":"Almawash","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics College of Pharmacy Shaqra University  Shaqra 11911 Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6372-9319","authenticated-orcid":false,"given":"Liga Hasan Mohammed","family":"Salim","sequence":"additional","affiliation":[{"name":"Public health Department Health Sciences College at Lieth Umm Al Qura University  Makkah 21955 Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8083-9145","authenticated-orcid":false,"given":"Alshebli","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Public health Department Health Sciences College at Lieth Umm Al Qura University  Makkah 21955 Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9274-7026","authenticated-orcid":false,"given":"Modawy Elnour Modawy","family":"Elkhalifa","sequence":"additional","affiliation":[{"name":"Public health Department Health Sciences College at Lieth Umm Al Qura University  Makkah 21955 Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,4]]},"reference":[{"key":"e_1_2_14_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2007.04.381"},{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-804766-8.00009-1"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.66.2.137"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(17)30159-X"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2007.04.381"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70223-4"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2016.07.150"},{"key":"e_1_2_14_8_1","first-page":"761","volume":"30","author":"Ullah F.","year":"2017","journal-title":"Pak. J. Pharm. Sci."},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201606210"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2023.155272"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.116786"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.619667"},{"key":"e_1_2_14_13_1","volume":"2","author":"Haass C.","year":"2012","journal-title":"Perspect. Med."},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2012.08.012"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.2174\/156802607779318262"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.2174\/138955708784223512"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11011-021-00683-x"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-013-0036-3"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta16210"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.200"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70119-8"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-7847.99898"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-824109-7.00012-1"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/1533317517717013"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200210070-00005"},{"key":"e_1_2_14_26_1","volume":"12","author":"Zhu F.","year":"2011","journal-title":"BMC Neurosci."},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1383038"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2007.00557.x"},{"key":"e_1_2_14_29_1","volume":"22","author":"Khan M. M.","year":"2012","journal-title":"Neurotoxicity Res."},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2014.10.044"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/979730"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70276-X"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2011.03.060"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/9783527805921.ch5"},{"key":"e_1_2_14_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2003.09.018"},{"key":"e_1_2_14_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2008.01.017"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1072994"},{"key":"e_1_2_14_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/aps.2017.28"},{"key":"e_1_2_14_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(01)00312-8"},{"key":"e_1_2_14_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2017.04.004"},{"key":"e_1_2_14_41_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar500152x"},{"key":"e_1_2_14_42_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00423"},{"key":"e_1_2_14_43_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2016.5103"},{"key":"e_1_2_14_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2011.10.004"},{"key":"e_1_2_14_45_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.108.021857"},{"key":"e_1_2_14_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2010.06751.x"},{"key":"e_1_2_14_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.11.043"},{"key":"e_1_2_14_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2012.02.016"},{"key":"e_1_2_14_49_1","doi-asserted-by":"publisher","DOI":"10.2174\/1567205015666180702105740"},{"key":"e_1_2_14_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2007.08.006"},{"key":"e_1_2_14_51_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/4606752"},{"key":"e_1_2_14_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2017.00353"},{"key":"e_1_2_14_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1799"},{"key":"e_1_2_14_54_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.173856"},{"key":"e_1_2_14_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2004.06.008"},{"key":"e_1_2_14_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.22340"},{"key":"e_1_2_14_57_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms12095592"},{"key":"e_1_2_14_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2010.01.012"},{"key":"e_1_2_14_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11596-020-2142-z"},{"key":"e_1_2_14_60_1","volume-title":"Amer Chemical Soc 1155 16TH ST","author":"Ho C.\u2010T.","year":"2019"},{"key":"e_1_2_14_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2015.10.036"},{"key":"e_1_2_14_62_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867311320100009"},{"key":"e_1_2_14_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2020.04.012"},{"key":"e_1_2_14_64_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01261"},{"key":"e_1_2_14_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trci.2018.09.009"},{"key":"e_1_2_14_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-008-7452-4"},{"key":"e_1_2_14_67_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf4000709"},{"key":"e_1_2_14_68_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.5b00214"},{"key":"e_1_2_14_69_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M404751200"},{"key":"e_1_2_14_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.10347"},{"key":"e_1_2_14_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2011.11.021"},{"key":"e_1_2_14_72_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11040756"},{"key":"e_1_2_14_73_1","doi-asserted-by":"publisher","DOI":"10.1017\/jns.2016.41"},{"key":"e_1_2_14_74_1","doi-asserted-by":"publisher","DOI":"10.1039\/b311404j"},{"key":"e_1_2_14_75_1","volume":"2","author":"Iriti M.","year":"2015","journal-title":"Recent Adv. Med. Chem."},{"key":"e_1_2_14_76_1","first-page":"1133104053","volume-title":"Advanced Nutrition and Human Metabolism: Cengage Learning","author":"Gropper S. S.","year":"2012"},{"key":"e_1_2_14_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2017.02.033"},{"key":"e_1_2_14_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(08)64021-2"},{"key":"e_1_2_14_79_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199655100-00008"},{"key":"e_1_2_14_80_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsptsci.0c00224"},{"key":"e_1_2_14_81_1","doi-asserted-by":"publisher","DOI":"10.1080\/13880209.2016.1231695"},{"key":"e_1_2_14_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(00)01159-9"},{"key":"e_1_2_14_83_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-006-9166-z"},{"key":"e_1_2_14_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.21588"},{"key":"e_1_2_14_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-015-1616-z"},{"key":"e_1_2_14_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-016-0380-7"},{"key":"e_1_2_14_87_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200502280-00013"},{"key":"e_1_2_14_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.20315"},{"key":"e_1_2_14_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2005.08.005"},{"key":"e_1_2_14_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2007.12.012"},{"key":"e_1_2_14_91_1","doi-asserted-by":"publisher","DOI":"10.1254\/jphs.CRJ04003X"},{"key":"e_1_2_14_92_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114508965776"},{"key":"e_1_2_14_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcb.2005.07.003"},{"key":"e_1_2_14_94_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2000.00265.x"},{"key":"e_1_2_14_95_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3580547"},{"key":"e_1_2_14_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(00)00510-4"},{"key":"e_1_2_14_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2011.09.010"},{"key":"e_1_2_14_98_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13668-018-0226-1"},{"key":"e_1_2_14_99_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0607822103"},{"key":"e_1_2_14_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2009.10.038"},{"key":"e_1_2_14_101_1","doi-asserted-by":"publisher","DOI":"10.1002\/asia.201601291"},{"key":"e_1_2_14_102_1","doi-asserted-by":"publisher","DOI":"10.1159\/000449482"},{"key":"e_1_2_14_103_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2003.01976.x"},{"key":"e_1_2_14_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2019.06.020"},{"key":"e_1_2_14_105_1","doi-asserted-by":"publisher","DOI":"10.1002\/asia.201201063"},{"key":"e_1_2_14_106_1","doi-asserted-by":"publisher","DOI":"10.1021\/cn400213r"},{"key":"e_1_2_14_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12263-007-0056-z"},{"key":"e_1_2_14_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2008.00344.x"},{"key":"e_1_2_14_109_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb-2023-0175"},{"key":"e_1_2_14_110_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2022-0217"},{"key":"e_1_2_14_111_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12010-023-04646-z"},{"key":"e_1_2_14_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.114872"},{"key":"e_1_2_14_113_1","doi-asserted-by":"publisher","DOI":"10.1039\/9781839167218-00133"},{"key":"e_1_2_14_114_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3994340"},{"key":"e_1_2_14_115_1","unstructured":"A. T.Khalil J.Iqbal A.Shah M. Z.Haque I.Khan M.Ayaz I.Ahmad S.Tasneem H.Shah 2021."},{"key":"e_1_2_14_116_1","volume-title":"Biogenic nanoparticles for cancer theranostics","author":"Patra C.","year":"2021"},{"key":"e_1_2_14_117_1","doi-asserted-by":"publisher","DOI":"10.2174\/9781681086378119050006"},{"key":"e_1_2_14_118_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13568-023-01527-w"},{"key":"e_1_2_14_119_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-018-8928-2"},{"key":"e_1_2_14_120_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.1046599"},{"key":"e_1_2_14_121_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-8977-7-3"},{"key":"e_1_2_14_122_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-36801-6"},{"key":"e_1_2_14_123_1","doi-asserted-by":"publisher","DOI":"10.3844\/ajassp.2010.480.485"},{"key":"e_1_2_14_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2011.02.008"},{"key":"e_1_2_14_125_1","doi-asserted-by":"publisher","DOI":"10.3109\/03639045.2015.1062897"},{"key":"e_1_2_14_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2011.10.002"},{"key":"e_1_2_14_127_1","doi-asserted-by":"publisher","DOI":"10.1021\/bc400055h"},{"key":"e_1_2_14_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2013.04.024"},{"key":"e_1_2_14_129_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-06115-9"},{"key":"e_1_2_14_130_1","doi-asserted-by":"publisher","DOI":"10.4103\/2230-973X.167661"},{"key":"e_1_2_14_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2010.05.005"},{"key":"e_1_2_14_132_1","volume":"1","author":"Illum L.","year":"2000","journal-title":"Eur. J. Pharm. Sci."},{"key":"e_1_2_14_133_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics10010034"},{"key":"e_1_2_14_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2013.05.009"},{"key":"e_1_2_14_135_1","doi-asserted-by":"publisher","DOI":"10.3109\/08982104.2014.899369"},{"key":"e_1_2_14_136_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S113171"},{"key":"e_1_2_14_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2013.03.037"},{"key":"e_1_2_14_138_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S39232"},{"key":"e_1_2_14_139_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S38378"},{"key":"e_1_2_14_140_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S596"},{"key":"e_1_2_14_141_1","volume":"8","author":"Vandenberghe R.","year":"2016","journal-title":"Alzheimer Res. Ther."},{"key":"e_1_2_14_142_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25163731"},{"key":"e_1_2_14_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2009.10.018"},{"key":"e_1_2_14_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2009.05.002"},{"key":"e_1_2_14_145_1","first-page":"S95","volume":"3","author":"Sultana F.","year":"2013","journal-title":"J. Appl. Pharm. Sci."},{"key":"e_1_2_14_146_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20040965"},{"key":"e_1_2_14_147_1","first-page":"45","volume-title":"Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices","author":"Trinh H. M.","year":"2017"},{"key":"e_1_2_14_148_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22020323"},{"key":"e_1_2_14_149_1","volume":"1","author":"\u00c7a\u011fda\u015f M.","year":"2014","journal-title":"Appl. Nanotechnol. Drug Deliv."},{"key":"e_1_2_14_150_1","doi-asserted-by":"publisher","DOI":"10.2217\/17435889.1.3.297"},{"key":"e_1_2_14_151_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S93918"},{"key":"e_1_2_14_152_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2017.00082"},{"key":"e_1_2_14_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajps.2018.09.005"},{"key":"e_1_2_14_154_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2017.00317"},{"key":"e_1_2_14_155_1","doi-asserted-by":"publisher","DOI":"10.1177\/014860710603000145"},{"key":"e_1_2_14_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-3988(09)60019-2"},{"key":"e_1_2_14_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.03.029"},{"key":"e_1_2_14_158_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S174072"},{"key":"e_1_2_14_159_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom9020056"},{"key":"e_1_2_14_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2016.01.006"},{"key":"e_1_2_14_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2014.04.050"},{"key":"e_1_2_14_162_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2011.06.015"},{"key":"e_1_2_14_163_1","doi-asserted-by":"publisher","DOI":"10.4172\/2157-7439.1000171"},{"key":"e_1_2_14_164_1","doi-asserted-by":"publisher","DOI":"10.1021\/mp900306x"},{"key":"e_1_2_14_165_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0032616"},{"key":"e_1_2_14_166_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.8b01921"},{"key":"e_1_2_14_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2018.11.008"},{"key":"e_1_2_14_168_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-012-9444-4"},{"key":"e_1_2_14_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2013.08.001"},{"key":"e_1_2_14_170_1","doi-asserted-by":"publisher","DOI":"10.2174\/2210303106666160120215857"},{"key":"e_1_2_14_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2015.06.025"},{"key":"e_1_2_14_172_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.10.027"},{"key":"e_1_2_14_173_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn405077y"},{"key":"e_1_2_14_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.10.024"},{"key":"e_1_2_14_175_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-43345-w"},{"key":"e_1_2_14_176_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-7158.2010.01225.x"},{"key":"e_1_2_14_177_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2007.12.001"},{"key":"e_1_2_14_178_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0082529"},{"key":"e_1_2_14_179_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.11.061"},{"key":"e_1_2_14_180_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2015.01.001"},{"key":"e_1_2_14_181_1","doi-asserted-by":"publisher","DOI":"10.1080\/13102818.2017.1347523"},{"key":"e_1_2_14_182_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S132472"},{"key":"e_1_2_14_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtice.2018.03.001"},{"key":"e_1_2_14_184_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13027-017-0145-6"},{"key":"e_1_2_14_185_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/145380"},{"key":"e_1_2_14_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2007.06.036"},{"key":"e_1_2_14_187_1","doi-asserted-by":"publisher","DOI":"10.1021\/am501341u"},{"key":"e_1_2_14_188_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.03.010"},{"key":"e_1_2_14_189_1","doi-asserted-by":"publisher","DOI":"10.1002\/iub.2330"},{"key":"e_1_2_14_190_1","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2018.2552"},{"key":"e_1_2_14_191_1","first-page":"42","volume":"22","author":"Nday C. M.","year":"2019","journal-title":"Hell. J. Nucl. Med."},{"key":"e_1_2_14_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2020.112696"},{"key":"e_1_2_14_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2016.03.002"},{"key":"e_1_2_14_194_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.2c00240"},{"key":"e_1_2_14_195_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2018.01.017"},{"key":"e_1_2_14_196_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-016-0136-4"},{"key":"e_1_2_14_197_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-016-0227-4"},{"key":"e_1_2_14_198_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2017.11.023"},{"key":"e_1_2_14_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2018.06.190"},{"key":"e_1_2_14_200_1","first-page":"32","volume":"22","author":"Nday C. M.","year":"2019","journal-title":"Hell. J. Nucl. Med."},{"key":"e_1_2_14_201_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2017.11.047"}],"container-title":["Molecular Nutrition &amp; Food Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mnfr.202400525","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T06:36:24Z","timestamp":1735194984000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.202400525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":201,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/mnfr.202400525"],"URL":"https:\/\/doi.org\/10.1002\/mnfr.202400525","archive":["Portico"],"relation":{},"ISSN":["1613-4125","1613-4133"],"issn-type":[{"value":"1613-4125","type":"print"},{"value":"1613-4133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-07-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2400525"}}