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The applied innovative formulations resulted in the desired changes in the distribution of gut microbiome species associated with T2DM, as revealed by QIIME2 and additionally confirmed by ANCOM. This effect was particularly pronounced in the curcumin\u2010supplemented formulation, as evident from the enrichment of the\n                    <jats:italic>Verrucomicrobiota<\/jats:italic>\n                    representative\n                    <jats:italic>Akkermansia muciniphila<\/jats:italic>\n                    and short\u2010chain fatty acid producers\n                    <jats:italic>Faecalibaculum<\/jats:italic>\n                    and\n                    <jats:italic>Dubosiella<\/jats:italic>\n                    , while also leading to a decrease in\n                    <jats:italic>Patescibacteria<\/jats:italic>\n                    , as well as\n                    <jats:italic>Chlamydia muridarum<\/jats:italic>\n                    ,\n                    <jats:italic>Desulfovibrio<\/jats:italic>\n                    ,\n                    <jats:italic>Candidatus Saccharimonas<\/jats:italic>\n                    , and\n                    <jats:italic>Alistipes<\/jats:italic>\n                    species. The administration of the examined innovative dietary fiber formulations statistically reduced the alpha diversity and altered the beta diversity of the gut microbiota in a mouse model with T2DM, in terms of abundance and presence of species analyzed with MicrobiomeAnalyst. Due to the strong influence on the composition of the gut microbiota, the innovative dietary formulations can be further evaluated for inclusion in food for special medical purposes specifically designed for the dietary management of diabetes.\n                  <\/jats:p>","DOI":"10.1002\/mnfr.70350","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T14:12:46Z","timestamp":1764771166000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Modulation of the Gut Microbiota of Diabetes\u2010Induced Mice Through Curcumin\u2010Enriched Dietary Fibers Intervention"],"prefix":"10.1002","volume":"70","author":[{"given":"Katarina","family":"Butorac","sequence":"first","affiliation":[{"name":"Laboratory For Antibiotic, Enzyme, Probiotic, and Starter Culture Technologies University of Zagreb Faculty of Food Technology and Biotechnology  Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Bani\u0107","sequence":"additional","affiliation":[{"name":"Laboratory For Antibiotic, Enzyme, Probiotic, and Starter Culture Technologies University of Zagreb Faculty of Food Technology and Biotechnology  Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jurica","family":"Zucko","sequence":"additional","affiliation":[{"name":"Laboratory For Bioinformatics University of Zagreb, Faculty of Food Technology and Biotechnology  Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreja","family":"Lebo\u0161 Pavunc","sequence":"additional","affiliation":[{"name":"Laboratory For Antibiotic, Enzyme, Probiotic, and Starter Culture Technologies University of Zagreb Faculty of Food Technology and Biotechnology  Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasna","family":"Novak","sequence":"additional","affiliation":[{"name":"Laboratory For Antibiotic, Enzyme, Probiotic, and Starter Culture Technologies University of Zagreb Faculty of Food Technology and Biotechnology  Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivanka","family":"Jeri\u0107","sequence":"additional","affiliation":[{"name":"Laboratory for Biomimetic Chemistry Ru\u0111er Bo\u0161kovi\u0107 Institute  Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tihomir","family":"Balog","sequence":"additional","affiliation":[{"name":"Laboratory for Metabolism and Aging Ru\u0111er Bo\u0161kovi\u0107 Institute  Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijeta","family":"Kralj","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental Therapy Ru\u0111er Bo\u0161kovi\u0107 Institute  Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenkica","family":"Penava","sequence":"additional","affiliation":[{"name":"Belupo, Pharmaceuticals &amp; 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