{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:07:06Z","timestamp":1791313626519,"version":"4.3.1"},"reference-count":96,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Nutrition Food Res"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Food structure has emerged as a critical concept with wide\u2010ranging implications for nutrition and health. Studies with in vitro digestion models are enabling a better fundamental understanding of the structure\u2013function relationships that define how food matrix properties change and influence nutrient release and transit during gastrointestinal digestion. Dietary lipids are of particular relevance due to their high energy density and associations with cardiometabolic risk, including postprandial rises in blood lipids. Studies using the dynamic TIM\u20101 digestion model enable investigations of fatty acid bioaccessibility, a precursor to lipid absorption, across a range of food products. This review presents the results of several investigations into food structure, with TIM\u20101 focusing on lipid digestion and instances where the findings correlate with corresponding human studies. Collectively, a better understanding of how food structure influences postprandial lipemia supports the development of food products tailored to benefit health.<\/jats:p>","DOI":"10.1002\/mnfr.70434","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T05:25:22Z","timestamp":1773638722000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The Role of Food Structure on Fatty Acid Bioaccessibility: A Decade of TIM\u20101 Simulated Digestion Studies in Review"],"prefix":"10.1002","volume":"70","author":[{"given":"Michael A.","family":"Rogers","sequence":"first","affiliation":[{"name":"Department of Food Science University of Guelph  Guelph ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda J.","family":"Wright","sequence":"additional","affiliation":[{"name":"Human Health and Nutritional Science University of Guelph  Guelph ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.5402\/2011\/936974"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/jns.2021.73"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.08.012"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2174\/157016111795495594"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-017-0568-5"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-021-01543-4"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182160726"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/1541-4337.13331"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/nutrit\/nuae103"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.90730.2008"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjnph-2024-001029"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu16244267"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0FO01506G"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41430-019-0459-0"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1322869"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2022.2142762"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2012.00317"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-56909-9_10"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/1750-3841.70049"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-814174-8.00002-0"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2023.2273448"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodhyd.2024.109736"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plipres.2017.10.001"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2023.2215873"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2022.02.028"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-food-032519-051646"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2024.1399534"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.18103\/mra.v10i9.3136"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2021.10.010"},{"key":"e_1_2_6_31_1","first-page":"S1","article-title":"Investigation of Lipid Digestion by Fungal and Porcine Lipase Supplements for Severe Pancreatic Insufficiency Using the \u201cIn Vitro\u201d Dynamic TIM Model","volume":"8","author":"Garcia T. 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