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LAB, including\n                    <jats:italic>Lacticaseibacillus<\/jats:italic>\n                    spp., are recognized as potential probiotics due to their ability to confer benefits to the host. Here we employ probiogenomic and in vitro analyses to characterize the probiotic potential of\n                    <jats:italic>Lc. paracasei<\/jats:italic>\n                    UFTM 2.9, a LAB that previously demonstrated probiotic properties in vitro. The draft genome of\n                    <jats:italic>Lc. paracasei<\/jats:italic>\n                    UFTM 2.9 comprises 127 contigs, totaling 3\u00a0216\u00a0252 base pairs, with a GC content of 46.20%. The bacteria showed metabolic versatility, growing in five carbon sources. A total of 170 genes potentially associated with probiotic characteristics were identified, with functions linked to stress resistance (\n                    <jats:italic>n<\/jats:italic>\n                    = 106), adhesion (\n                    <jats:italic>n<\/jats:italic>\n                    = 12), biosynthesis of vitamins (\n                    <jats:italic>n<\/jats:italic>\n                    = 10), and others. No virulence genes or CRISPR elements were detected, and two phages were identified in\n                    <jats:italic>Lc. paracasei<\/jats:italic>\n                    UFTM 2.9. Gene clusters encoding bacteriocins were detected and confirmed in vitro.\n                    <jats:italic>L<\/jats:italic>\n                    <jats:italic>c. paracasei<\/jats:italic>\n                    UFTM 2.9 inhibited all indicator bacteria tested (\n                    <jats:italic>n<\/jats:italic>\n                    = 12), including strains of\n                    <jats:italic>Listeria innocua<\/jats:italic>\n                    ,\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    ,\n                    <jats:italic>Streptococcus agalactiae<\/jats:italic>\n                    , and\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    . The results indicate the potential use of\n                    <jats:italic>Lc. paracasei<\/jats:italic>\n                    UFTM 2.9 as a probiotic, considering its genetic potential to express traits of interest and survive in the gastrointestinal tract (GIT).\n                  <\/jats:p>","DOI":"10.1002\/mnfr.70441","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T14:41:32Z","timestamp":1774017692000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unveiling the Probiotic Properties of\n                    <i>Lacticaseibacillus paracasei<\/i>\n                    UFTM 2.9 Through Probiogenomic Analysis"],"prefix":"10.1002","volume":"70","author":[{"given":"B\u00e1rbara R.","family":"Fonseca","sequence":"first","affiliation":[{"name":"Federal University of Juiz de Fora, Minas Gerais Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin N. V.","family":"Sabino","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora, Minas Gerais Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz M. O.","family":"Rocha","sequence":"additional","affiliation":[{"name":"Federal University of Santa Catarina Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasco A. C.","family":"Azevedo","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais (UFMG) Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertram","family":"Brenig","sequence":"additional","affiliation":[{"name":"Georg August University G\u00f6ttingen  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siomar C.","family":"Soares","sequence":"additional","affiliation":[{"name":"Federal University of Tri\u00e2ngulo Mineiro (UFTM) Uberaba Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro N.","family":"Lemos","sequence":"additional","affiliation":[{"name":"Ilum School of Science, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, S\u00e3o Paulo, Brazil Campinas S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia Bordalo","family":"Tonucci","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora, Minas Gerais Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila C. P. D.","family":"Luquetti","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora, Minas Gerais Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline D.","family":"Paiva","sequence":"additional","affiliation":[{"name":"Federal University of Tri\u00e2ngulo Mineiro (UFTM) Uberaba Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julliane D.","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora, Minas Gerais Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3972-7576","authenticated-orcid":false,"given":"Alessandra B. 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