{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T07:45:01Z","timestamp":1792395901910,"version":"4.4.0"},"reference-count":61,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Nutrition Food Res"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Selenium plays an important role in antioxidant defense and metabolic regulation. This study evaluated the effects of dietary supplementation with non\u2010enriched and selenium\u2010enriched\n                    <jats:italic>Pleurotus ostreatus<\/jats:italic>\n                    mushrooms, as well as selenized yeast, on selenium deposition and antioxidant responses in piglets, a relevant model for human nutrition. Sixty\u2010four weaned piglets were fed control or supplemented diets for 21 days. Growth performance was not affected, indicating that the treatments were well tolerated. Selenium was higher in the loin of the supplemented groups than in the control group, whereas selenium concentration in the liver showed a numerical, but nonsignificant, increase in supplemented groups (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.08), and no differences were observed in the kidney. Hepatic antioxidant activity was differentially modulated by dietary treatments. Glutathione peroxidase activity increased in all supplemented groups, whereas catalase activity increased only in piglets receiving selenium\u2010enriched mushroom or selenized yeast, and superoxide dismutase activity increased only in the selenium\u2010enriched mushroom group. Nitrite levels were reduced in all supplemented groups, while plasma antioxidant parameters remained unchanged. These findings indicate that dietary supplementation modulated hepatic antioxidant responses, although the relative contributions of selenium enrichment and mushroom bioactive compounds could not be determined.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial Registration Number and Date of Registration<\/jats:bold>\n                    : 106\/2018\n                  <\/jats:p>","DOI":"10.1002\/mnfr.70609","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:33:48Z","timestamp":1790753628000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Antioxidant Responses to Dietary Supplementation With Non\u2010Enriched and Selenium\u2010Enriched Mushrooms and Selenized Yeast in Piglets"],"prefix":"10.1002","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2805-5703","authenticated-orcid":false,"given":"Diene 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Oliveira","family":"Porto","sequence":"additional","affiliation":[{"name":"Institute of Chemistry Universidade de S\u00e3o Paulo (USP)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1483-8288","authenticated-orcid":false,"given":"Pedro Vitoriano","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Institute of Chemistry Universidade de S\u00e3o Paulo (USP)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4678-7876","authenticated-orcid":false,"given":"Marliane de C\u00e1ssia Soares","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of Microbiology Universidade Federal de Vi\u00e7osa (UFV)  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9539-9370","authenticated-orcid":false,"given":"Maria Catarina Megumi","family":"Kasuya","sequence":"additional","affiliation":[{"name":"Department of Microbiology Universidade Federal de Vi\u00e7osa (UFV)  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7821-3191","authenticated-orcid":false,"given":"Maiane de Paula","family":"Alves","sequence":"additional","affiliation":[{"name":"Department of Microbiology Universidade Federal de Vi\u00e7osa (UFV)  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique Renon","family":"Eller","sequence":"additional","affiliation":[{"name":"Department of Food Technology Universidade Federal de Vi\u00e7osa (UFV)  Vi\u00e7osa Minas Gerais 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