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The objective of the current work is to identify and assess the dose\u2013response of food intake biomarkers of green beans. In an acute intervention study, 27 participants consumed green beans in the study center and urine samples were collected pre\u2010 and post\u2010consumption. Metabolites were measured by nuclear magnetic resonance (\n                    <jats:sup>1<\/jats:sup>\n                    H\u2010NMR) and liquid chromatography\u2013mass spectrometry (LC\u2013MS). Statistical analysis determined features that changed post\u2010consumption of green beans. Selected metabolites were assessed for dose\u2013response in a follow\u2010up study (\n                    <jats:italic>n<\/jats:italic>\n                    = 16). Analysis revealed 745\n                    <jats:sup>1<\/jats:sup>\n                    H\u2010NMR spectral regions and 318 LC\u2013MS features that increased in intensity over time following consumption of green beans. Three\n                    <jats:sup>1<\/jats:sup>\n                    H\u2010NMR and 12 LC\u2013MS metabolites displayed a dose\u2013response relationship to increasing portion size of green beans (\n                    <jats:italic>p<\/jats:italic>\n                    &lt;0.05), including amino acid conjugates (glycine conjugate, N\u2010phenylacetylglutamine), hydroxyabscisic acid glucuronide and amino\u2010hydroxybenzoic acid. Partial least squares discriminant analysis predicted low or high green bean intake with 91.6% accuracy. We identified 15 urinary food intake biomarkers of green beans. A biomarker panel classified individuals as low or high green bean consumers with good accuracy, progressing ongoing efforts to improve dietary assessment methods.\n                  <\/jats:p>","DOI":"10.1002\/mnfr.70625","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T07:21:26Z","timestamp":1791789686000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Metabolomics Based Biomarkers of Green Beans Intake"],"prefix":"10.1002","volume":"70","author":[{"given":"Rebecca","family":"Finlay","sequence":"first","affiliation":[{"name":"UCD School of Agriculture and Food Science Institute of Food and Health University College Dublin  Dublin Ireland"},{"name":"UCD Conway Institute University College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya","family":"Gao","sequence":"additional","affiliation":[{"name":"UCD School of Agriculture and Food Science Institute of Food and Health University College Dublin  Dublin Ireland"},{"name":"UCD Conway Institute University College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"},{"name":"Channing Division of Network Medicine Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Epidemiology Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"},{"name":"Channing Division of Network Medicine Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayne","family":"Woodside","sequence":"additional","affiliation":[{"name":"Centre For Public Health Queens University Belfast  Belfast UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"Yin","sequence":"additional","affiliation":[{"name":"UCD School of Agriculture and Food Science Institute of Food and Health University College Dublin  Dublin Ireland"},{"name":"UCD Conway Institute University College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Brennan","sequence":"additional","affiliation":[{"name":"UCD School of Agriculture and Food Science Institute of Food and Health University College Dublin  Dublin 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