{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T12:30:11Z","timestamp":1770553811390,"version":"3.49.0"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T00:00:00Z","timestamp":1520294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01|B13001"],"award-info":[{"award-number":["01|B13001"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["LA 2804\/6\u20101"],"award-info":[{"award-number":["LA 2804\/6\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate the extent of <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> image distortions in the pelvis caused by susceptibility\u2010induced field inhomogeneities in <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> images in the context of a study on <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010guided radiotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using a high\u2010bandwidth double\u2010echo gradient echo sequence, field maps and distortion maps of the pelvis were calculated and evaluated for 219 exams (92 of female and 127 of male patients) to investigate patient\u2010related image distortions caused by susceptibility differences in an ongoing study on <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010guided radiotherapy. The evaluation of distortions in the regions \u201crectum\u201d, \u201cprostate\u201d, \u201ccervix\u201d, and in a reference region in the gluteus maximus was based on masks drawn by two readers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Distortions in the prostate and cervix were smaller than 0.03\u00a0px (0.1\u00a0mm) for 99% of voxels, and reached a maximum value of 0.09\u00a0px (0.3\u00a0mm). In the reference region, maximum distortions were smaller than in the prostate and cervix.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Using a geometric uncertainty of 0.2\u00a0px (0.6\u00a0mm) in margin definition for organs that are close to the rectum like the prostate and the cervix would be a cautious choice to account for susceptibility\u2010induced distortions that can arise during <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010based treatment guidance for the imaging setting used in this study. Since distortions are inversely proportional to the readout bandwidth of the sequence, safety margins need to be adapted adequately. Additional sources of image distortions like gradient nonlinearities are not included in our margin recommendations and should be considered separately.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mp.12785","type":"journal-article","created":{"date-parts":[[2018,2,2]],"date-time":"2018-02-02T18:52:35Z","timestamp":1517597555000},"page":"1586-1593","source":"Crossref","is-referenced-by-count":10,"title":["Technical Note: On the size of susceptibility\u2010induced <scp>MR<\/scp> image distortions in prostate and cervix in the context of <scp>MR<\/scp>\u2010guided radiation therapy"],"prefix":"10.1002","volume":"45","author":[{"given":"Julian","family":"Emmerich","sequence":"first","affiliation":[{"name":"Department of Medical Physics in Radiology German Cancer Research Center (DKFZ) Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederik B.","family":"Laun","sequence":"additional","affiliation":[{"name":"Department of Medical Physics in Radiology German 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