{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:39:38Z","timestamp":1767706778441},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,7,14]],"date-time":"2019-07-14T00:00:00Z","timestamp":1563062400000},"content-version":"am","delay-in-days":345,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T00:00:00Z","timestamp":1533254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1557679"],"award-info":[{"award-number":["1557679"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000121","name":"Division of Mathematical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000121","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["1R01CA214825\u201001"],"award-info":[{"award-number":["1R01CA214825\u201001"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P50 CA097007\u201010"],"award-info":[{"award-number":["P50 CA097007\u201010"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011676","name":"Elekta","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011676","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) provides noninvasive evaluation of patient's anatomy without using ionizing radiation. Due to this and the high soft\u2010tissue contrast, <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> use has increased and has potential for use in longitudinal studies where changes in patients\u2019 anatomy or tumors at different time points are compared. Deformable image registration can be useful for these studies. Here, we describe two datasets that can be used to evaluate the registration accuracy of systems for <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> images, as it cannot be assumed to be the same as that measured on <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Acquisition and validation methods<\/jats:title><jats:p>Two sets of images were created to test registration accuracy. (a) A porcine phantom was created by placing ten 0.35\u2010mm gold markers into porcine meat. The porcine phantom was immobilized in a plastic container with movable dividers. T1\u2010weighted, T2\u2010weighted, and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> images were acquired with the porcine phantom compressed in four different ways. The markers were not visible on the <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> images, due to the selected voxel size, so they did not interfere with the measured registration accuracy, while the markers were visible on the <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> images and were used to identify the known deformation between positions. (b) Synthetic images were created using 28 head and neck squamous cell carcinoma patients who had <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> scans pre\u2010, mid\u2010, and postradiotherapy treatment. An inter\u2010 and intrapatient variation model was created using these patient scans. Four synthetic pretreatment images were created using the interpatient model, and four synthetic post\u2010treatment images were created for each of the pretreatment images using the intrapatient model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data format and usage notes<\/jats:title><jats:p>The T1\u2010weighted, T2\u2010weighted, and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scans of the porcine phantom in the four positions are provided. Four T1\u2010weighted synthetic pretreatment images each with four synthetic post\u2010treatment images, and four T2\u2010weighted synthetic pretreatment images each with four synthetic post\u2010treatment images are provided. Additionally, the applied deformation vector fields to generate the synthetic post\u2010treatment images are provided. The data are available on <jats:styled-content style=\"fixed-case\">TCIA<\/jats:styled-content> under the collection <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">DIR<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Potential applications<\/jats:title><jats:p>The proposed database provides two sets of images (one acquired and one computer generated) for use in evaluating deformable image registration accuracy. T1\u2010 and T2\u2010weighted images are available for each technique as the different image contrast in the two types of images may impact the registration accuracy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mp.13090","type":"journal-article","created":{"date-parts":[[2018,7,14]],"date-time":"2018-07-14T16:04:24Z","timestamp":1531584264000},"page":"4315-4321","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Synthetic head and neck and phantom images for determining deformable image registration accuracy in magnetic resonance imaging"],"prefix":"10.1002","volume":"45","author":[{"given":"Rachel B.","family":"Ger","sequence":"first","affiliation":[{"name":"Department of Radiation Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"},{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinzhong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Radiation Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"},{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Imaging Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan C.","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"},{"name":"Department of Imaging Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos E.","family":"Cardenas","sequence":"additional","affiliation":[{"name":"Department of Radiation Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"},{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clifton D.","family":"Fuller","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"},{"name":"Department of Radiation Oncology The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca M.","family":"Howell","sequence":"additional","affiliation":[{"name":"Department of Radiation Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"},{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiation Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"},{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Jason","family":"Stafford","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"},{"name":"Department of Imaging Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shouhao","family":"Zhou","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"},{"name":"Department of Biostatistics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence E.","family":"Court","sequence":"additional","affiliation":[{"name":"Department of Radiation Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"},{"name":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Houston TX 77030 USA"},{"name":"Department of Imaging Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,3]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"Organization for Economic Co\u2010operation and Development.Magnetic resonance imaging (MRI) exams.https:\/\/data.oecd.org\/healthcare\/magnetic-resonance-imaging-mri-exams.htm."},{"key":"e_1_2_8_3_1","first-page":"E537","article-title":"Longitudinal studies","volume":"7","author":"Caruana EJ","year":"2015","journal-title":"J Thor Dis"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.14132871"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.4769114"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.07.677"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/50\/12\/011"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/726268"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/54\/7\/001"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.1915012"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2007.01.056"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.2965263"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.08.021"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.1806292"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.1288241"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2002.808367"},{"key":"e_1_2_8_17_1","unstructured":"LiX AbramsonRG ArlinghausLR et\u00a0al.Data from QIN\u2010breast. The Cancer Imaging Archive;2016."},{"key":"e_1_2_8_18_1","unstructured":"ShahN FengX LankerovichM PuchalskiRB KeoghB.Data from Ivy GAP. The Cancer Imaging Archive;2016."},{"key":"e_1_2_8_19_1","unstructured":"NewittD HyltonN Team obotI\u2010SNaAT.Multi\u2010center breast DCE\u2010MRI data and segmentations from patients in the I\u2010SPY 1\/ACRIN 6657 trials. The Cancer Imaging Archive;2016."},{"key":"e_1_2_8_20_1","unstructured":"HuangW TudoricaA ChuiS et\u00a0al.Variations of dynamic contrast\u2010enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge. The Cancer Imaging Archive;2014."},{"key":"e_1_2_8_21_1","unstructured":"HuangW RyanC BeckettB et\u00a0al.Data From QIN\u2010SARCOMA. The Cancer Imaging Archive;2016."},{"key":"e_1_2_8_22_1","unstructured":"BarboriakD.Data from RIDER_NEURO_MRI. The Cancer Imaging Archive;2015."},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn.2009.21407"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.12.044"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/mp.12406"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1120\/jacmp.v17i1.5888"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep29864"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-11554-w"}],"container-title":["Medical Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmp.13090","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mp.13090","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mp.13090","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/am-pdf\/10.1002\/mp.13090","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mp.13090","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T09:25:17Z","timestamp":1695029117000},"score":1,"resource":{"primary":{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/10.1002\/mp.13090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,3]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1002\/mp.13090"],"URL":"https:\/\/doi.org\/10.1002\/mp.13090","archive":["Portico"],"relation":{},"ISSN":["0094-2405","2473-4209"],"issn-type":[{"value":"0094-2405","type":"print"},{"value":"2473-4209","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,3]]},"assertion":[{"value":"2017-11-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}