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X\u2010ray dose distributions and depth\u2010dose profiles were calculated using a Monte Carlo simulation. The performances of the applicators were evaluated by measuring and analyzing the dosimetric characteristics of x rays generated from the miniature x\u2010ray tube equipped with the applicators.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Quite uniform dose distributions around the applicators were achieved by optimizing the dwell positions and the dwell times of the miniature x\u2010ray tube inside the applicators. In addition, identical absolute dose and depth\u2010dose profiles were obtained through the control of the <jats:styled-content style=\"fixed-case\">IFP<\/jats:styled-content> values even though different\u2010sized applicators are used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The presented 3D printing technique provides an efficient approach to provide vaginal applicators with optimal <jats:styled-content style=\"fixed-case\">IFP<\/jats:styled-content>s that allow consistent treatment time for patients of varying vaginal canal size.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mp.13335","type":"journal-article","created":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T09:14:25Z","timestamp":1544692465000},"page":"448-455","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Three\u2010dimensional\u2010printed vaginal applicators for electronic brachytherapy of endometrial cancers"],"prefix":"10.1002","volume":"46","author":[{"given":"Ju Hyuk","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and Technology Daejeon 305\u2010701 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Nam","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and Technology Daejeon 305\u2010701 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung San","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and Technology Daejeon 305\u2010701 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Oh","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and Technology Daejeon 305\u2010701 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21442"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2014.0025"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2013.05.033"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-26791-3"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20140146"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2452061983"},{"key":"e_1_2_8_8_1","first-page":"313","article-title":"Pre\u2010operative, post\u2010operative and exclusive irradiation of endometrial adenocarcinoma","volume":"170","author":"Pernot M","year":"1994","journal-title":"Strahlenther Onkol"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.12.079"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)00689-1"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20150002"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.2357021"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.01.082"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1556-276X-7-258"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brachy.2008.05.003"},{"key":"e_1_2_8_16_1","first-page":"24","article-title":"Basic and advanced materials for fused deposition modeling rapid prototyping technology","volume":"11","author":"Novakova\u2010Marcincinova L","year":"2012","journal-title":"Manuf Ind Eng"},{"key":"e_1_2_8_17_1","unstructured":"PerezM BlockM EspalinD et\u00a0al.Sterilization of FDM\u2010manufactured parts. 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