{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T11:51:58Z","timestamp":1780487518106,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T00:00:00Z","timestamp":1556755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Color images are visualized on medical monitors that are adjusted by a grayscale standard display function (<jats:styled-content style=\"fixed-case\">GSDF<\/jats:styled-content>) or <jats:italic>\u03b3<\/jats:italic>2.2. Although the <jats:styled-content style=\"fixed-case\">GSDF<\/jats:styled-content> is visually displayed as a linear graded grayscale, it does not specify how color medical images should be presented. On the other hand, the usual gamma setting for color images is <jats:italic>\u03b3<\/jats:italic>2.2, but it has not been standardized. The color standard display function (<jats:styled-content style=\"fixed-case\">CSDF<\/jats:styled-content>) has recently been proposed as a standardized gamma setting for color medical monitors. However, the influence of various gamma settings on image characteristics should be determined. The present study aimed to identify differences in color\u2010scale characteristics on nuclear medicine images displayed on medical monitors adjusted by <jats:styled-content style=\"fixed-case\">CSDF<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> GSDF<\/jats:styled-content>, and <jats:italic>\u03b3<\/jats:italic>2.2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Transverse normal (n\u00a0=\u00a01) and abnormal (n\u00a0=\u00a05) brain perfusion images were generated using a mathematical digital phantom. Transverse phantom and clinical brain images are shown using the clinically applied eight\u2010color scale. Five nuclear medicine experts visually assessed phantom and clinical images using a defect severity scale that ranged from zero (no defect) to four (defect). Receiver operating characteristic curves were created and areas under the curves (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>s) were analyzed. Defect scores for the clinical study were evaluated in the nine segments on basal ganglia slice, and defect scores were summed for each patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average defect score for color A significantly differed in multiple comparison tests, but not in <jats:italic>post hoc<\/jats:italic> tests. The ranges of <jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content> for <jats:styled-content style=\"fixed-case\">CSDF<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> GSDF<\/jats:styled-content>, and <jats:italic>\u03b3<\/jats:italic>2.2 were 0.86\u20130.94, 0.82\u20130.94, and 0.88\u20130.97, respectively. The <jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>s of <jats:styled-content style=\"fixed-case\">CSDF<\/jats:styled-content> in all color scales did not significantly differ from other gamma settings. The summed defect scores of <jats:styled-content style=\"fixed-case\">CSDF<\/jats:styled-content> were similar to those of other gamma settings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Nuclear medicine images were equally valid when adjusted by <jats:styled-content style=\"fixed-case\">CSDF<\/jats:styled-content> even at various gamma settings. Nuclear medicine images can be evaluated equally using any gamma setting. Nonetheless, the color gamma setting for medical monitors should be standardized.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mp.13532","type":"journal-article","created":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T01:01:54Z","timestamp":1555030914000},"page":"2580-2588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of calibration methods for color medical displays on interpreting brain <scp>SPECT<\/scp> images"],"prefix":"10.1002","volume":"46","author":[{"given":"Takayuki","family":"Shibutani","sequence":"first","affiliation":[{"name":"Department of Quantum Medical Technology Institute of Medical, Pharmaceutical and Health Sciences Kanazawa University Kanazawa Ishikawa 920\u20100942 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahisa","family":"Onoguchi","sequence":"additional","affiliation":[{"name":"Department of Quantum Medical Technology Institute of Medical, Pharmaceutical and Health Sciences Kanazawa University Kanazawa Ishikawa 920\u20100942 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroto","family":"Yoneyama","sequence":"additional","affiliation":[{"name":"Department of Radiological Technology Kanazawa University Hospital Kanazawa Ishikawa 920\u20108641 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Functional Imaging and Artificial Intelligence Kanazawa University Kanazawa Ishikawa 920\u20108641 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinro","family":"Matsuo","sequence":"additional","affiliation":[{"name":"Matsuo Medical Clinic Hirakata Osaka 573\u20101152 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Bamba","sequence":"additional","affiliation":[{"name":"EIZO Corporation Hakusan Ishikawa 924\u20108566 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Saito","sequence":"additional","affiliation":[{"name":"EIZO Corporation Hakusan Ishikawa 924\u20108566 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,5,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-005-1779-y"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-009-1266-y"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1071-3581(97)90059-3"},{"key":"e_1_2_8_5_1","first-page":"1941","article-title":"Three\u2010dimensional color\u2010modulated display of myocardial SPECT perfusion distributions accurately assesses coronary artery disease","volume":"41","author":"Santana CA","year":"2000","journal-title":"J Nucl Med"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10916-016-0478-5"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nuclcard.2007.06.115"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1067\/mnc.2001.110388"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.1861159"},{"key":"e_1_2_8_10_1","unstructured":"Japan Medical Imaging and Radiological Systems Industries Association (JIRA).Japan Industries Association of Radiological Systems Standards (JESRA) X\u20100093*B\u22122017Quality Assurance (QA) Guidelines for Medical Imaging Display Systems.http:\/\/www.jira-net.or.jp\/publishing\/files\/jesra\/JESRA_X-0093B_2017.pdf. 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