{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T18:06:57Z","timestamp":1704823617532},"reference-count":41,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T00:00:00Z","timestamp":1561507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81771854","11874049"],"award-info":[{"award-number":["81771854","11874049"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007225","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007225","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Guided waves generated from bone cortex inevitably act on microbubbles flowing through skeletal muscle capillaries in contrast\u2010enhanced ultrasound (CEUS) and might influence the image quality. However, the action mechanism underlying the guided waves influence is still unknown, especially under contrast pulse\u2010inversion transmission mode. This study aimed to clarify the influence of guided waves on pulse\u2010inversion CEUS, which was investigated via <jats:italic>in vitro<\/jats:italic> infusion experiments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Tibia guided waves were detected at pulse\u2010inversion transmission and then characterized by using a short\u2010time Fourier transform energy distribution. Using results at normal incidence as a baseline, the influence of guided wave dispersion on the contrast and resolution of pulse\u2010inversion CEUS was investigated at an oblique incidence through continuous microbubbles infusion experiments in a vessel\u2013tibia flow phantom.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Frequency\u2010dispersive property of tibia guided waves was observed at phases 0\u00b0 and 180\u00b0, which improved the contrast of CEUS and reduced its resolution. Pulse\u2010inversion CEUS balanced the contrast enhancement and resolution degeneration induced by guided waves. By contrast, contrast\u2010to\u2010tissue ratio of pulse\u2010inversion CEUS increased by up to 109.1\u00a0\u00b1\u00a013.2% (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05) due to guided waves and its resolution was up to 0.9\u00a0\u00b1\u00a00.1 times that of baseline.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Alterations of contrast and resolution in pulse\u2010inversion CEUS induced by guided waves might provide an additional assessment for the capillary perfusion in the skeletal muscle near the bone cortex.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mp.13634","type":"journal-article","created":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T16:23:18Z","timestamp":1559233398000},"page":"3475-3482","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Influence of guided waves in bone on pulse\u2010inversion contrast\u2010enhanced ultrasound"],"prefix":"10.1002","volume":"46","author":[{"given":"Diya","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, School of Life Science and Technology Xi\u2019an Jiaotong University Xi\u2019an 710049 China"},{"name":"University of Montreal Hospital Research Center Montreal H2X 0A9 Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, School of Life Science and Technology Xi\u2019an Jiaotong University Xi\u2019an 710049 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuchao","family":"Sang","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, School of Life Science and Technology Xi\u2019an Jiaotong University Xi\u2019an 710049 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Qu","sequence":"additional","affiliation":[{"name":"University of Montreal Hospital Research Center Montreal H2X 0A9 Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Oncology Beijing Friendship Hospital Capital Medical University Beijing 100050 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Ultrasonic Diagnosis The Second Hospital of Jilin University Changchun 130041 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingxi","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, School of Life Science and Technology Xi\u2019an Jiaotong University Xi\u2019an 710049 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,26]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Ultrasound Contrast Agents: Basic Principles and Clinical Application","author":"Goldberg BB","year":"2001"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-624X(99)00071-2"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2011.05.003"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2009.09.009"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2005.24.4.431"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-8389(05)70292-X"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2012.31.5.737"},{"key":"e_1_2_6_9_1","first-page":"203","article-title":"Value of high resolution ultrasound and contrast enhanced US pulse inversion imaging for the evaluation of the vascular integrity of free\u2010flap grafts","volume":"36","author":"Prantl L","year":"2007","journal-title":"Clin Hemorheol Micro"},{"key":"e_1_2_6_10_1","first-page":"35","article-title":"Improvements in high resolution ultrasound for postoperative investigation of capillary microperfusion after free tissue transfer","volume":"43","author":"Lamby P","year":"2009","journal-title":"Clin Hemorheol Micro"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2015.10.006"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","unstructured":"WangD ZhangY HuH LiuR ZhongH WanM.Influences of frequency\u2010dispersive guided waves on contrast\u2010enhanced ultrasound imaging.Paper presented at: IEEE International Ultrasonics Symposium (IUS) 2016; 1\u20104.","DOI":"10.1109\/ULTSYM.2016.7728729"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-624X(99)00148-1"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-624X(01)00080-4"},{"key":"e_1_2_6_15_1","unstructured":"deJongN BouakazA FrinkingP.Harmonic imaging for ultrasound contrast agents. Paper presented at: IEEE International Ultrasonics Symposium (IUS) 2000;1869\u20131876."},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mp.12897"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2009.09.002"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(00)00229-5"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1109\/58.753026"},{"key":"e_1_2_6_20_1","first-page":"1","article-title":"Contrast enhanced ultrasound (CEUS) and time intensity curve (TIC) analysis in compartment syndrome: first results","volume":"50","author":"Geis S","year":"2012","journal-title":"Clin Hemorheol Micro"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-010-1779-3"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1088\/0967-3334\/23\/4\/313"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1109\/TUFFC.2008.790"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2006.02.001"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2008.10.007"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.2973228"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2013.06.007"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep43628"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2008.12.003"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2018.07.018"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3733"},{"key":"e_1_2_6_32_1","doi-asserted-by":"crossref","unstructured":"LindnerG FaustmannH KrempelS MunchM RothballerS SingerF.Wave propagation in an acoustic wave guide sensor for liquids driven by pulsed excitation of surface acoustic waves. Paper presented at: IEEE International Frequency Control Symposium;2008:39\u201343.","DOI":"10.1109\/FREQ.2008.4622952"},{"key":"e_1_2_6_33_1","doi-asserted-by":"crossref","unstructured":"SchmittM SchmidtK TietzeS LindnerG.Detection of droplets on non\u2010piezoelectric substrates via mode conversion of lamb waves. Paper presented at: Proceedings Sensoren und Messsysteme.2010:298\u2013305.","DOI":"10.1109\/ICSENS.2010.5689878"},{"key":"e_1_2_6_34_1","doi-asserted-by":"crossref","unstructured":"WanY ZhangS ZongY WanM.Formation of two\u2010way lamb waves and force potential wells using single conventional ultrasonic transducer. Paper presented at: Proceedings of Meetings on Acoustics.2012;15:045003.","DOI":"10.1121\/1.4736740"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1109\/58.883539"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2016.02.002"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2014.01.004"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(05)80004-1"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.3685482"},{"key":"e_1_2_6_40_1","unstructured":"WangD YangX WanJ JingB ZhangL WanM.Ultrasound contrast plane wave imaging with higher CTR based on pulse inversion bubble wavelet transform. Paper presented at: IEEE International Ultrasonics Symposium (IUS).2014;1\u20134."},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/mp.13097"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1109\/TUFFC.2009.1161"}],"container-title":["Medical Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmp.13634","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mp.13634","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mp.13634","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mp.13634","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T03:11:15Z","timestamp":1693624275000},"score":1,"resource":{"primary":{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/10.1002\/mp.13634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,26]]},"references-count":41,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1002\/mp.13634"],"URL":"https:\/\/doi.org\/10.1002\/mp.13634","archive":["Portico"],"relation":{},"ISSN":["0094-2405","2473-4209"],"issn-type":[{"value":"0094-2405","type":"print"},{"value":"2473-4209","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,26]]},"assertion":[{"value":"2018-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}