{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T05:31:59Z","timestamp":1782279119383,"version":"3.54.5"},"reference-count":47,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study is to calculate setup margin based on six\u2010dimensional (6D) corrected residual positional errors from kV cone beam computed tomography (CBCT) and from intrafraction projection kV imaging in coplanar and in noncoplanar couch positions in stereotactic radiotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Six dimensional positional corrections were carried out before patient treatments, using a robotic couch and CBCT matching. A CBCT and stereoscopic ExacTrac image were acquired post\u2010table position correction. Further, a series of intrafraction ExacTrac images were obtained for the variable couch position. Translational and rotational errors were identified as lateral (X), longitudinal (Y), vertical (Z); roll (\u019f\u00b0), pitch (\u03a6\u00b0) and yaw (\u03a8\u00b0). A total of 699 intrafraction image sets (361 coplanar and 338 noncoplanar) for 51 SRS\/SRT patients were analysed. Rotational errors were corrected in terms of translational coordinates. Residual set\u2010up margins were calculated from CBCT shifts. ExacTrac shifts give residual\u00a0+\u00a0intrafraction setup margins as a function of coplanar and noncoplanar couch\u00a0positions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average residual positional error obtained from CBCT in X, Y, Z, \u019f, \u03a6, \u03a8 were 0.1\u00a0\u00b1\u00a00.4\u00a0mm, 0.0\u00a0\u00b1\u00a00.6\u00a0mm,\u00a00.0\u00a0\u00b1\u00a00.5\u00a0mm, 0.2\u00a0\u00b1\u00a00.8\u00b0, 0.1\u00a0\u00b1\u00a00.6\u00b0 and \u22120.1\u00a0\u00b1\u00a00.7\u00b0 respectively. For ExacTrac, the shits were \u22120.5\u00a0\u00b1\u00a00.9\u00a0mm, \u22120.0\u00a0\u00b1\u00a01mm, \u22120.6\u00a0\u00b1\u00a01.0mm, 0.4\u00a0\u00b1\u00a00.9\u00b0, \u22120.2\u00a0\u00b1\u00a00.6\u00b0, and \u22120.0\u00a0\u00b1\u00a00.8\u00b0.<\/jats:p><jats:p>CBCT calculated linear setup margins in X, Y, Z direction were 0.5, 1.2, and 1\u00a0mm respectively. ExacTrac yielded coplanar and noncoplanar linear setup margins were 1.2, 1.3, 1.5, 1.4, 1.5, and 2.1\u00a0mm respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CBCT\u2010based gross residual set\u2010up margin is equal to 1\u00a0mm. ExacTrac calculated residual plus intrafraction setup margin falls within a 2\u00a0mm range; attributed to intrafraction patient movement, table position inaccuracies, and poor image fusion in noncoplanar geometry. There could be variations in the required additional margin between centers and between machines, which require further studies.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mp.13810","type":"journal-article","created":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T06:15:40Z","timestamp":1568009740000},"page":"4749-4754","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Technical Note: Rotational positional error corrected intrafraction set\u2010up margins in stereotactic radiotherapy: A spatial assessment for coplanar and noncoplanar geometry"],"prefix":"10.1002","volume":"46","author":[{"given":"Biplab","family":"Sarkar","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Manipal Hospitals Dwarka New Delhi 110070 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anusheel","family":"Munshi","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology 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