{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T03:39:59Z","timestamp":1790480399511,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The pursuit of adaptive radiotherapy using MR imaging for better precision in patient positioning puts stringent demands on the hardware components of the MR scanner. Particularly in particle therapy, the dose distribution and thus the efficacy of the treatment is susceptible to beam attenuation from interfering materials in the irradiation path. This severely limits the usefulness of conventional imaging coils, which contain highly attenuating parts such as capacitors and preamplifiers in an unknown position, and requires development of a dedicated radiofrequency (RF) coil with close consideration of the materials and components used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>In MR\u2010guided radiation therapy in the human torso, imaging coils with a large FOV and homogeneous B<jats:sub>1<\/jats:sub> field distribution are required for reliable tissue classification. In this work, an imaging coil for MR\u2010guided particle therapy was developed with minimal ion attenuation while maintaining flexibility in treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A birdcage coil consisting of nearly radiation\u2010transparent materials was designed and constructed for a closed\u2010bore 1.5 T MR system. Additionally, the coil was mounted on a rotatable patient capsule for flexible positioning of the patient relative to the beam. The ion attenuation of the RF coil was investigated in theory and via measurements of the Bragg peak position. To characterize the imaging quality of the RF coil, transmit and receive field distributions were simulated and measured inside a homogeneous tissue\u2010simulating phantom for various rotation angles of the patient capsule ranging from 0\u00b0 to 345\u00b0 in steps of 15\u00b0. Furthermore, simulations with a heterogeneous human voxel model were performed to better estimate the effect of real patient loading, and the RF coil was compared to the internal body coil in terms of SNR for a full rotation of the patient capsule.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The RF coil (total water equivalent thickness (WET) \u2248 420\u00a0\u00b5m, WET of conductor \u2248 210\u00a0\u00b5m) can be considered to be radiation\u2010transparent, and a measured transmit power efficiency (B<jats:sub>1<\/jats:sub><jats:sup>+<\/jats:sup>\/) between 0.17 \u00b5T\/ and 0.26 \u00b5T\/ could be achieved in a volume (\u0394z\u00a0=\u00a0216\u00a0mm, complete x and y range) for the 24 investigated rotation angles of the patient capsule. Furthermore, homogeneous transmit and receive field distributions were measured and simulated in the transverse, coronal and sagittal planes in a homogeneous phantom and a human voxel model. In addition, the SNR of the radiation\u2010transparent RF coil varied between 103 and 150, in the volume (\u0394z\u00a0=\u00a0216\u00a0mm) of a homogeneous phantom and surpasses the SNR of the internal body coil for all rotation angles of the patient capsule.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A radiation\u2010transparent RF coil was developed and built that enables flexible patient to beam positioning via full rotation capability of the RF coil and patient relative to the beam, with results providing promising potential for adaptive MR\u2010guided particle therapy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mp.17065","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T10:24:43Z","timestamp":1713954283000},"page":"4028-4043","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["An essentially radiation\u2010transparent body coil integrated with a patient rotation system for MR\u2010guided particle therapy"],"prefix":"10.1002","volume":"51","author":[{"given":"Kilian A.","family":"Dietrich","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Heidelberg University Hospital  Heidelberg Germany"},{"name":"Medical Physics in Radiology German Cancer Research Center (DKFZ)  Heidelberg Germany"},{"name":"Faculty of Physics Heidelberg University  Heidelberg Germany"},{"name":"Clinical Cooperation Unit Radiation Oncology German Cancer Research Center (DKFZ)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Kl\u00fcter","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Heidelberg University Hospital  Heidelberg Germany"},{"name":"National Center for Radiation Research in Oncology (NCRO)  Heidelberg Germany"},{"name":"Heidelberg Institute of Radiation Oncology (HIRO)  Heidelberg 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