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In this study, the NPWE model observer is used to detect specific tasks (circular designer nodules) ranging between 1 and 30\u00a0mm in diameter using chest and abdomen phantom images acquired across the diagnostic energy range (60\u2013125 kVp) with and without an anti\u2010scatter grid.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study was to derive tube voltage (kVp) settings that return maximal NPWE detectability (d\u2019) of designer nodules, for digital radiography (DR) chest and abdomen imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Images of a chest phantom (LucAl phantom) and a surrogate for an abdomen (18.5\u00a0cm PMMA) were acquired across the diagnostic energy range (60\u2013125 kVp) with matched effective dose (for the respective anatomies), with and without an anti\u2010scatter grid, on a general x\u2010ray system. Images were captured using an Agfa DX\u2010D 40C wireless indirect caesium iodide (CsI) imaging panel. Modulation transfer function (MTF), normalized noise power spectrum (NNPS), and contrast (C) were measured in each image and the detectability index d\u2019 was calculated for circular designer nodules with diameters ranging from 1 to 30\u00a0mm (in steps of 1\u00a0mm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The calculated d\u2019 peaked at a nodule diameter of 3\u00a0mm irrespective of tube voltage, for both chest and abdomen images. A tube voltage of 80\u00a0kVp returned maximal d\u2019 for chest imaging across all nodule diameters both with and without an anti\u2010scatter grid. A tube voltage of 70 kVp returned maximal d\u2019 for abdomen imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The NPWE observer model has been used to derive tube voltages (kVp) that return maximal detectability (d\u2019) of designer nodules for chest and abdomen radiography using a modern DR imaging system. This will provide the medical physicist with a starting point in the task of optimising tube voltage range for chest and abdomen imaging.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mp.17477","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T16:08:39Z","timestamp":1729699719000},"page":"146-157","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Tube voltage in chest and abdomen DR imaging: Which settings return maximal non\u2010prewhitening model observer with eye filter (NPWE) detectability?"],"prefix":"10.1002","volume":"52","author":[{"given":"Craig S.","family":"Moore","sequence":"first","affiliation":[{"name":"Medical Physics Department Queen's Centre for Oncology and Haematology Castle Hill Hospital Hull University Teaching Hospitals NHS Trust  Hull UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim J.","family":"Wood","sequence":"additional","affiliation":[{"name":"Medical Physics Department Queen's Centre for Oncology and Haematology Castle Hill Hospital Hull University Teaching Hospitals NHS Trust  Hull UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Saunderson","sequence":"additional","affiliation":[{"name":"Medical Physics Department Queen's Centre for Oncology and Haematology Castle Hill Hospital Hull University Teaching Hospitals NHS Trust  Hull UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew W.","family":"Beavis","sequence":"additional","affiliation":[{"name":"Medical Physics Department Queen's Centre for Oncology and Haematology Castle Hill Hospital Hull University Teaching Hospitals NHS Trust  Hull UK"},{"name":"Clinical Sciences Centre Hull York Medical School University of Hull  Hull UK"},{"name":"Department of Medical Physics and Biomedical Engineering University College London, Malet Place Engineering Building  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,23]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"The Ionising Radiation (Medical Exposure) Regulations 2017. 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