{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T05:48:18Z","timestamp":1788241698186,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T00:00:00Z","timestamp":1735862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DFG GRK 2274"],"award-info":[{"award-number":["DFG GRK 2274"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A significant proportion of false positive recalls of mammography\u2010screened women is due to benign breast cysts and simple fibroadenomas. These lesions appear mammographically as smooth\u2010shaped dense masses and require the recalling of women for a breast ultrasound to obtain complementary imaging information. They can be identified safely by ultrasound with no need for further assessment or treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Grating\u2010based x\u2010ray dark\u2010field breast imaging allows contrast formation based on both attenuation and small\u2010angle x\u2010ray scattering and provides complementary imaging information in one single acquisition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Experiments with ex\u2010vivo mastectomy samples were performed with a three\u2010grating Talbot\u2010Lau interferometer using a laboratory\u2010based polychromatic x\u2010ray source. Attenuation and dark\u2010field images were correlated to clinical mammography and complementary diagnostic imaging techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Benign breast lesions with homogeneous internal structures such as fibroadenomas and simple fluid\u2010filled cysts, typically presenting as dense breast lesions in standard mammography, showed a signal drop in the dark\u2010field image. Complicated cysts provided a higher dark\u2010field signal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results presented show that grating\u2010based x\u2010ray dark\u2010field mammography could provide complementary imaging information in one single acquisition, eliminating the need for a second examination to identify harmless cysts and simple fibroadenomas.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mp.17603","type":"journal-article","created":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T16:09:50Z","timestamp":1735920590000},"page":"2145-2154","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Grating\u2010based x\u2010ray dark\u2010field mammography: Assessing complementary imaging information in simple cystic lesions and typical fibroadenoma"],"prefix":"10.1002","volume":"52","author":[{"given":"Karin","family":"Hellerhoff","sequence":"first","affiliation":[{"name":"Breast 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