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In this study, beam\u2010quality correction factors,\n                      <jats:italic>k<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      , for He, C, and Ne ions in five types of ionization chambers were derived through Monte Carlo simulations. Additionally, perturbation effects attributed to the ionization chambers were analyzed in detail, and differences in these effects across chamber types and ions were clarified.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:italic>k<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      values for 150 MeV\/u\u2010He, 290 MeV\/u\u2010C, and 400 MeV\/u\u2010Ne ions were evaluated using the Geant4 Monte Carlo code. The\n                      <jats:italic>f<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      (the product of the water\u2010to\u2010air stopping power ratio and the perturbation correction factor) was obtained using the absorbed doses to water and to air inside the active volume of the ionization chamber. The\n                      <jats:italic>k<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      values were then calculated from the\n                      <jats:italic>f<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      and the literature\u2010extracted factors,  and\n                      <jats:italic>W<\/jats:italic>\n                      <jats:sub>air<\/jats:sub>\n                      . To evaluate individual perturbation effects, each chamber component (such as the central electrode, wall, and stem in the modeled chambers) was replaced by water in turn, and the dose was recalculated for each modified geometry. From the ratio of these doses, the contribution of each component to the perturbation effect was estimated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The derived\n                      <jats:italic>k<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      values were consistent with the code of practice for dosimetry, the revised TRS\u2010398, and varied slightly with the ion species, from He to Ne ions. Additionally, the\n                      <jats:italic>k<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      values increased by up to 1% compared with the current protocol values, particularly in plane\u2010parallel chambers. Analysis of contributions to the perturbation factors revealed that the perturbation effect due to the cavity,\n                      <jats:italic>P<\/jats:italic>\n                      <jats:sub>cav<\/jats:sub>\n                      , is significantly greater for light ions than for protons and had the most substantial impact among the evaluated individual perturbation factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The revision of\n                      <jats:italic>k<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      values for light ions may result in the absorbed dose\u2010to\u2010water varying by up to 1% compared with doses calculated using the currently recommended\n                      <jats:italic>k<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      values. At the current stage, it has been confirmed that common\n                      <jats:italic>k<\/jats:italic>\n                      <jats:sub>Q<\/jats:sub>\n                      values can be applied to light ions from He to Ne in both Farmer and Markus type ionization chambers.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mp.70024","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T03:45:09Z","timestamp":1758253509000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Monte Carlo\u2013calculated beam\u2013quality and perturbation correction factors for helium\u2013, carbon\u2013, and neon\u2013ion beams"],"prefix":"10.1002","volume":"52","author":[{"given":"Yuka","family":"Urago","sequence":"first","affiliation":[{"name":"QST Hospital National Institutes for Quantum Science and Technology (QST)  Chiba Japan"},{"name":"National Institute of Advanced Industrial Science and Technology (AIST) National Metrology Institute of Japan  Ibaraki Japan"},{"name":"Department of Radiological Science Graduate School of Human Health Science Tokyo Metropolitan University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Sakama","sequence":"additional","affiliation":[{"name":"QST Hospital National Institutes for Quantum Science and Technology (QST)  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dousatsu","family":"Sakata","sequence":"additional","affiliation":[{"name":"National Institute of Advanced Industrial Science and Technology (AIST) National Metrology Institute of Japan  Ibaraki Japan"},{"name":"Division of Health Sciences Osaka University  Osaka Japan"},{"name":"School of Physics University of Bristol  Bristol UK"},{"name":"Centre for Medical Radiation Physics University of Wollongong  Wollongong New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsurou","family":"Katayose","sequence":"additional","affiliation":[{"name":"Division of Medical Physics Chiba Cancer Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weishan","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Radiological Science Graduate School of Human Health Science Tokyo Metropolitan University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","unstructured":"PirruccelloMC TobiasCA.Biological and medical research with accelerated heavy ions at the Bevalac 1977\u20101980. 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