{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T10:36:43Z","timestamp":1768214203914,"version":"3.49.0"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Swallowing\u2010induced anatomical motion can compromise the accuracy of head\u2010and\u2010neck radiotherapy, underscoring the need for proactive motion management. Because tongue motion precedes laryngeal displacement, it may serve as a predictive signal for swallowing onset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To develop and evaluate a real\u2010time tongue\u2010motion monitoring system and assess its utility for predicting swallowing\u2010induced motion in radiotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The system comprised a gas\u2010pressure module that measures intra\u2010oral pressure (a surrogate for tongue motion) and an IR\u2010marker tracking module for laryngeal motion. Reliability testing (accuracy and repeatability) was conducted for both modules. Synchronized acquisition was verified by analyzing peak\u2010time differences between paired signals to exclude inter\u2010module delay. A volunteer study (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a014) quantified the temporal relationship between intra\u2010oral pressure and laryngeal motion.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The developed real\u2010time tongue\u2010motion monitoring system demonstrated reliable performance. In volunteers, tongue motion consistently preceded laryngeal motion, with per\u2010volunteer medians of 0.405\u20130.805 s (predominantly 0.5\u20130.7 s), supporting its validity as a predictive signal for swallowing onset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Real\u2010time tongue\u2010motion monitoring provides a predictive signal for swallowing onset and can aid management of swallowing\u2010induced motion in head\u2010and\u2010neck radiotherapy. By enabling early detection of swallowing events, the system has the potential to reduce dose\u2010delivery errors and improve treatment accuracy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mp.70137","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T04:35:06Z","timestamp":1764304506000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of a real\u2010time tongue motion monitoring system for managing swallowing\u2010induced motion in neck cancer radiation therapy"],"prefix":"10.1002","volume":"52","author":[{"given":"Tae\u2010Ho","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Yonsei Cancer Center Heavy Ion Therapy Research Institute Yonsei University College of Medicine  Seoul South 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