{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T13:42:06Z","timestamp":1788183726004,"version":"build-2803163510"},"reference-count":64,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["2024\u201005355"],"award-info":[{"award-number":["2024\u201005355"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To develop clinically relevant test cases for commissioning Model\u2010Based Dose Calculation Algorithms (MBDCAs) for\n                      <jats:sup>192<\/jats:sup>\n                      Ir High Dose Rate (HDR) gynecologic brachytherapy following the workflow proposed by the TG\u2010186 report and the WGDCAB report 372.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Acquisition and validation methods<\/jats:title>\n                    <jats:p>\n                      Two cervical cancer intracavitary HDR brachytherapy models were developed based on a real patient, using either uniformly structured regions or realistic segmentation. The patient's computed tomography (CT) images were processed, converted to a series of digital imaging and communications in medicine (DICOM) CT images, and imported into two treatment planning systems (TPSs), the Oncentra Brachy and BrachyVision. The original segmentation of the clinical case was augmented to enable a thorough dosimetric analysis. The actual clinical treatment plan was generally maintained, with the source replaced by a generic\n                      <jats:sup>192<\/jats:sup>\n                      Ir HDR source. Dose to medium in medium calculations were performed using the MBDCA option of each TPS, and three different Monte Carlo (MC) simulation codes. MC results demonstrated agreement within statistical uncertainty, while comparisons between the commercial TPS MBDCAs and a general\u2010purpose MC code highlighted both the advantages and limitations of the studied MBDCAs, suggesting potential approaches to overcome the challenges.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data format and usage notes<\/jats:title>\n                    <jats:p>\n                      The datasets for the developed cases are available online at\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/doi.org\/10.5281\/zenodo.15720996\">https:\/\/doi.org\/10.5281\/zenodo.15720996<\/jats:ext-link>\n                      . The DICOM files include the treatment plan for each case, TPS, and the corresponding reference MC dose data. The package also contains a TPS\u2010 and case\u2010specific user guide for commissioning the MBDCAs, as well as files necessary to replicate the MC simulations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Potential applications<\/jats:title>\n                    <jats:p>The provided datasets and proposed methodology can serve as a commissioning framework for TPSs that employ MBDCAs, as well as a benchmark for brachytherapy researchers using MC methods and MBDCA developers. They also facilitate intercomparisons of MBDCA performance and provide a quality assurance resource for evaluating future TPS software updates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mp.70260","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T02:45:12Z","timestamp":1767926712000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical test cases for commissioning, QA, and benchmarking of model\u2010based dose calculation algorithms in\n                    <sup>1<\/sup>\n                    \u2079\n                    <sup>2<\/sup>\n                    Ir HDR gynecologic tandem and ring brachytherapy"],"prefix":"10.1002","volume":"53","author":[{"given":"Vasiliki","family":"Peppa","sequence":"first","affiliation":[{"name":"Medical Physics Laboratory, Medical School National and Kapodistrian University of Athens  Athens Greece"},{"name":"Radiotherapy Department General Hospital of Athens Alexandra  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maude","family":"Robitaille","sequence":"additional","affiliation":[{"name":"Medical Physics Unit, Department of Oncology, Faculty of Medicine McGill University  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Akbari","sequence":"additional","affiliation":[{"name":"Carleton Laboratory for Radiotherapy Physics, Physics Department Carleton University  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirin A.","family":"Enger","sequence":"additional","affiliation":[{"name":"Medical Physics Unit, Department of Oncology, Faculty of Medicine McGill University  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rowan M.","family":"Thomson","sequence":"additional","affiliation":[{"name":"Carleton Laboratory for Radiotherapy Physics, Physics Department Carleton University  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Firas","family":"Mourtada","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sidney Kimmel Cancer Center Thomas Jefferson University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel P.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Developmental Biology Maastricht University Medical Centre+  Maastricht The 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