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These test cases address the limits of the standard TG\u201043 formalism towards improving dose evaluations in prostate cancer treatment, in accordance with the recommendations of the joint Task Group 186 of the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Acquisition and Validation Methods<\/jats:title>\n                    <jats:p>Six test scenarios using the I\u2010125 OncoSeed 6711 were simulated with three Monte Carlo codes: EGSnrc application egs_brachy with eb_gui, MCNP with BrachyGuide, and PenRed. The test cases range from basic, e.g., single seed in water, to more complex configurations, e.g., 58 seeds in a virtual patient model for prostate treatment. The virtual model was developed from anonymized CT\u2010based images, representing a real patient with and without calcifications. Dose comparisons were performed using both local and global metrics, with eb_gui as the reference for validation. For all test cases, the local agreement of Monte Carlo codes was within \u223c3.0% and the global agreement was 0.01%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Format and Usage Notes<\/jats:title>\n                    <jats:p>\n                      The dataset, including Monte Carlo input files and other required information, is available online at\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/doi.org\/10.5281\/zenodo.15282647\">https:\/\/doi.org\/10.5281\/zenodo.15282647<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Potential Applications<\/jats:title>\n                    <jats:p>The developed test cases provide an essential resource for the development, validation, and commissioning of MBDCAs. They have the potential to improve dosimetric accuracy in complex prostate implants while also providing a platform for future brachytherapy research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mp.70309","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T14:55:22Z","timestamp":1770735322000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Generation of 3D reference dosimetric datasets towards adoption of model\u2010based dose calculations for permanent implant prostate brachytherapy"],"prefix":"10.1002","volume":"53","author":[{"given":"Fatemeh","family":"Akbari","sequence":"first","affiliation":[{"name":"Carleton Laboratory for Radiotherapy Physics Physics Department Carleton University  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliki","family":"Peppa","sequence":"additional","affiliation":[{"name":"Medical Physics Laboratory Medical School National and Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Ouellet","sequence":"additional","affiliation":[{"name":"Carleton Laboratory for Radiotherapy Physics Physics Department Carleton University  Ottawa Ontario Canada"},{"name":"D\u00e9partement de physique de g\u00e9nie physique et d'optique et Centre de recherche sur le cancer Universit\u00e9 Laval  Qu\u00e9bec Canada"},{"name":"Service de radio\u2010oncologie et Axe Oncologie du CRCHU de Qu\u00e9bec CHU de Qu\u00e9bec\u2010Universit\u00e9 Laval  Quebec QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narjes","family":"Moghadam","sequence":"additional","affiliation":[{"name":"Carleton Laboratory for Radiotherapy Physics Physics Department Carleton University  Ottawa Ontario 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