{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T14:19:22Z","timestamp":1788272362308,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFF0507800"],"award-info":[{"award-number":["2024YFF0507800"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFF0507804"],"award-info":[{"award-number":["2024YFF0507804"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62422123"],"award-info":[{"award-number":["62422123"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["12505357"],"award-info":[{"award-number":["12505357"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A20284"],"award-info":[{"award-number":["U23A20284"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Most recently, a novel color\u2010encoding light\u2010field detector based on perovskite material has been demonstrated for x\u2010ray differential phase contrast (DPC) imaging. However, it lacks performance evaluation and comparison between such a novel light\u2010field detector and a widely used grating interferometer before applying it into medical imaging field.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aims at evaluating and comparing the DPC imaging performance of the light\u2010field detector and the grating\u00a0interferometer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this work, a mathematical signal model was developed for the color\u2010encoding perovskite light\u2010field detector designed for x\u2010ray DPC imaging. Specifically, the beam refraction angle was modeled based on the changes in the emitted color within the standard CIE1931 color space. Upon it, noise responses were derived. Numerical simulations were conducted to compare the sensitivity and signal variance of the perovskite light\u2010field detector with those of a generic grating interferometer system. Additionally, impacts of the polychromatic x\u2010ray beam and the Compton scattering were also\u00a0investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>It was found that the sensitivity of the perovskite light\u2010field detector may surpass that of the grating interferometer if its color depth exceeds 30\u2010bit (three 10\u2010bit color channels). For perovskite light\u2010field detectors, the signal noise increases as the detected refraction signal increases. In addition, polychromatic x\u2010ray beam adds bias to the retrieved DPC signal, but has slight impact on the signal noise. Compton scattered x\u2010ray photons could dramatically change the retrieved DPC\u00a0signal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study demonstrates that the novel perovskite light\u2010field detector may not be suitable for medical grade DPC imaging due to the inevitable Compton scatters. However, it might be a promising alternative to the grating interferometer in developing state\u2010of\u2010the\u2010art scientific DPC imaging instruments for small sample (), in which the impact of Compton scatters could be\u00a0ignored.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mp.70601","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T02:29:09Z","timestamp":1785378549000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Theoretical modeling and numerical simulation of a light\u2010field detector for x\u2010ray differential phase contrast imaging"],"prefix":"10.1002","volume":"53","author":[{"given":"Yuhang","family":"Tan","sequence":"first","affiliation":[{"name":"Research Center for Advanced Detection Materials and Medical Imaging Devices, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences  Shenzhen Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiongtao","family":"Zhu","sequence":"additional","affiliation":[{"name":"Research Center for Advanced Detection Materials and Medical Imaging Devices, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences  Shenzhen Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Research Center for Advanced Detection Materials and Medical Imaging Devices, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences  Shenzhen Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hairong","family":"Zheng","sequence":"additional","affiliation":[{"name":"Paul C Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen Guangdong China"},{"name":"State Key Laboratory of Biomedical Imaging Science and System 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