{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T22:40:22Z","timestamp":1699828822966},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":10426,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med. Pediatr. Oncol."],"published-print":{"date-parts":[[1978,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Nine patients with \u201climited\u201d (thoracic) small\u2010cell lung carcinoma were treated with combined chemotherapy and radiotherapy (involved field and prophylactic whole brain). Induction drugs were Vincristine, Adriamycin, and Cyclophosphamide; and Cyclophosphamide, Vincristine, and CCNU for maintenance. Eight out of nine patients (89%) continue NED at a median follow\u2010up time of 12 months. This group is compared to 21 patients with more extensive disease and 6 patients with limited disease using various other regimens. Median survival in the extensive group was 5 months and 8 months for the limited\u2010diseased group treated with single agents. Intensive combination chemo\u2010irradiation therapy is safe and highly effective in patients with limited oat\u2010cell carcinoma of the lung, and leads to prolonged disease\u2010free survival.<\/jats:p>","DOI":"10.1002\/mpo.2950040413","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T14:58:34Z","timestamp":1171983514000},"page":"363-366","source":"Crossref","is-referenced-by-count":0,"title":["Treatment of oat\u2010cell carcinoma of the lung in the community"],"prefix":"10.1002","volume":"4","author":[{"given":"Ronald","family":"Citronbaum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"333","article-title":"Advances in small\u2010cell bronchogenic carcinoma","volume":"61","author":"Bunn PA","year":"1977","journal-title":"Cancer Treat Rep"},{"key":"e_1_2_1_3_2","first-page":"285","article-title":"Small\u2010cell carcinoma of the lung: Attempt to remedy causes of past therapeutic failure","volume":"2","author":"Johnson RE","year":"1976","journal-title":"Lancet"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.235.12.1225"},{"key":"e_1_2_1_5_2","first-page":"925","article-title":"Cyclophosphamide and CCNU in the treatment of inoperable small\u2010cell carcinoma and adenocarcinoma of the lung","volume":"60","author":"Edmonson JH","year":"1976","journal-title":"Cancer Treat Rep"},{"key":"e_1_2_1_6_2","first-page":"1","article-title":"Combined modality therapy for oat\u2010cell carcinoma of the lung: A randomized trial","volume":"61","author":"Alexander M","year":"1977","journal-title":"Cancer Treat Rep"}],"container-title":["Medical and Pediatric Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmpo.2950040413","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mpo.2950040413","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T22:05:59Z","timestamp":1699826759000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mpo.2950040413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,1]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1978,1]]}},"alternative-id":["10.1002\/mpo.2950040413"],"URL":"https:\/\/doi.org\/10.1002\/mpo.2950040413","archive":["Portico"],"relation":{},"ISSN":["0098-1532","1096-911X"],"issn-type":[{"value":"0098-1532","type":"print"},{"value":"1096-911X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,1]]}}}