{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:32:51Z","timestamp":1784194371414,"version":"3.55.0"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":10426,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med. Pediatr. Oncol."],"published-print":{"date-parts":[[1978,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Alpha\u2010hemolytic Streptococci were associated with 29 episodes of sepsis (12 polymicrobial) in 27 patients with cancer during a nine year period. Only two patients had dental manipulation prior to the onset of sepsis, but each had received chemotherapy and 75% were granulocytopenic (PMN &lt; 500\/mm<jats:sup>3<\/jats:sup>) at the time of the infection. None of the patients developed bacterial endocarditis. Unlike the normal host in whom a transient bacteria with alpha\u2010hemolytic Streptococci may occur following dental extraction or periodontal procedures, the cancer patient is at risk for more clinically significant sepsis. This risk is probably related to the presence of chemotherapy\u2010induced oral mucusitis and granulocytopenia, and our results suggests that isolation of alpha\u2010hemolytic Streptococci in febrile cancer patients should not be dismissed as a contaminent.<\/jats:p>","DOI":"10.1002\/mpo.2950040414","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T14:58:34Z","timestamp":1171983514000},"page":"367-370","source":"Crossref","is-referenced-by-count":38,"title":["Alpha\u2010hemolytic streptococci: Clinical significance in the cancer patient"],"prefix":"10.1002","volume":"4","author":[{"given":"P. A.","family":"Pizzo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Ladisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. G.","family":"Witebsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"55","article-title":"Presence of various types of non\u2010hemolytic Streptococci in dental plaque and in other sites of the oral cavity in man","volume":"18","author":"Carlsson J","year":"1967","journal-title":"Odontol Revy"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-9-3-275"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(49)90261-5"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(54)90071-7"},{"key":"e_1_2_1_6_2","first-page":"549","article-title":"Transient bacteremia after dental manipulation","volume":"122","author":"Kaplan EL","year":"1971","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1542\/peds.51.3.476","article-title":"Transient bacteremia during dental manipulation in children","volume":"51","author":"Berry FA","year":"1972","journal-title":"Pediatrics"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(74)90157-1"},{"key":"e_1_2_1_9_2","first-page":"125","article-title":"Streptococcus salvarius, Streptococcus sanguis, and Streptococcus \u201cmitis\u201d as indicators of contamination of root canal cultures with saliva","volume":"26","author":"Mejare B","year":"1975","journal-title":"Odontol Revy"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1128\/jcm.5.2.184-201.1977","article-title":"Physiological differentiation of the viridans Streptocci","volume":"5","author":"Facklam RR","year":"1977","journal-title":"J Clin Microbiol"},{"key":"e_1_2_1_11_2","volume-title":"Streptococci and Streptococcal Diseases: Recognition, Understanding, and Management","author":"Colman A","year":"1972"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/002203457605500108011"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(75)91760-2"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.71.2.229"}],"container-title":["Medical and Pediatric Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmpo.2950040414","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mpo.2950040414","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T22:06:39Z","timestamp":1699826799000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mpo.2950040414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,1]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1978,1]]}},"alternative-id":["10.1002\/mpo.2950040414"],"URL":"https:\/\/doi.org\/10.1002\/mpo.2950040414","archive":["Portico"],"relation":{},"ISSN":["0098-1532","1096-911X"],"issn-type":[{"value":"0098-1532","type":"print"},{"value":"1096-911X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,1]]}}}