{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T03:10:33Z","timestamp":1699845033831},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,20]],"date-time":"2006-07-20T00:00:00Z","timestamp":1153353600000},"content-version":"vor","delay-in-days":9331,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med. Pediatr. Oncol."],"published-print":{"date-parts":[[1981,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Reports of acute nonlymphoblastic leukemia occurring after successful treatment of Hodgkin and non\u2010Hodgkin lymphoma (NHL) are appearing with increasing frequency. Two years after completion of LSA<jats:sup>2<\/jats:sup>\u2010L<jats:sup>2<\/jats:sup> therapy for stage III, poorly differentiated lymphocytic lymphoma, a 16\u2010year\u2010old boy developed a preleukemic state characterized by a refractory macrocytic anemia with excess blasts, dyshematopoiesis, abnormal cluster:colony ratio on in vitro bone marrow culture, and acquired deficiencies of erythrocyte pyruvate kinase, triose phosphate isomerase, and adenylate kinase. Four months later acute myeloblastic leukemia was evident. The RNA index determined by flow cytofluorometry was increased. Four marker chromosomes were found and involved complex translocation of chromosomes 11 and 17 (t11;17) in 100% of the cells, and chromosome 4 (t4q;4) in 10% of the cells.<\/jats:p><jats:p>A thorough literature search uncovered four other reports of acute nonlymphoblastic leukemia occurring in children treated for NHL and a total of 58 cases in the adult and pediatric age groups. Over 50% of the patients had AML, were men over 50 years of age, and were treated with radiotherapy and chemotherapy. It is anticipated that additional cases of second malignancies will be reported in this population of patients whose outlook for the curability of the primary malignancy is 75%.<\/jats:p>","DOI":"10.1002\/mpo.2950090110","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T15:03:18Z","timestamp":1171983798000},"page":"69-80","source":"Crossref","is-referenced-by-count":7,"title":["Acute myeloblastic leukemia following non\u2010hodgkin lymphoma in an adolescent. A report of a case with preleukemic syndrome, and review of the literature"],"prefix":"10.1002","volume":"9","author":[{"given":"Prakash","family":"Kaur","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis R.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Andreeff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raju","family":"Chaganti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul A.","family":"Meyers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197211302872204"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(75)90600-2"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197909)44:3<1070::AID-CNCR2820440341>3.0.CO;2-1"},{"key":"e_1_2_1_5_2","first-page":"297","article-title":"Acute leukemia as a terminal event in nonleukemic hematopoietic disorders","volume":"3","author":"Bloomfield CD","year":"1976","journal-title":"Semin Oncol"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950010307"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950070206"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1182\/blood.V44.1.1.1","article-title":"Agar culture studies in 127 cases of untreated acute leukemia. The prognostic value of reclassification of leukemia according to in vitro growth characteristics","volume":"44","author":"Moore MAS","year":"1974","journal-title":"Blood"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90201-7"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1182\/blood.V55.2.282.282","article-title":"Melamed MR: Discrimination of human leukemic subtypes by flow cytometric analysis of cellular DNA and RNA","volume":"55","author":"Andreeff M","year":"1980","journal-title":"Blood"},{"key":"e_1_2_1_11_2","volume-title":"A Manual of Biochemical Methods","author":"Beutler E","year":"1975"},{"key":"e_1_2_1_12_2","volume-title":"An International System for Human Cytogenetic Nomenclature (1978)","author":"ISCN","year":"1978"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.128.5.802"},{"key":"e_1_2_1_14_2","first-page":"866","article-title":"Apparition d'une leucemie mueloide aigue au cours de l'evolution d'un lymphosarcome","volume":"99","author":"Gosselin G","year":"1970","journal-title":"Z\/un. Med u Can"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000207721"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197612)38:6<2557::AID-CNCR2820380646>3.0.CO;2-U"},{"key":"e_1_2_1_17_2","first-page":"71","article-title":"Development of acute leukemia in a patient with lymphosarcoma","volume":"78","author":"Gunz FW","year":"1975","journal-title":"NZ Med J"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197211)30:5<1275::AID-CNCR2820300520>3.0.CO;2-4"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-53-1-221"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-40-6-1217"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197901000-00002"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1148\/115.1.179"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.134.4.728"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197103)27:3<579::AID-CNCR2820270311>3.0.CO;2-Q"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196102000-00002"},{"key":"e_1_2_1_26_2","first-page":"227","article-title":"Reticulum cell sarcoma terminating in acute leukemia","volume":"15","author":"Zeffern JL","year":"1960","journal-title":"Blood"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1967)20:4<545::AID-CNCR2820200412>3.0.CO;2-0"},{"key":"e_1_2_1_28_2","first-page":"24","article-title":"The development of myeloid leukemia in a case of lymphosarcoma","volume":"27","author":"Pal AK","year":"1973","journal-title":"Indian J Med"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197912)44:6<2316::AID-CNCR2820440647>3.0.CO;2-6"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197807)42:1<229::AID-CNCR2820420137>3.0.CO;2-A"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950070403"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197808)42:2 <854::AID-CNCR2820420707>3.0.CO;2-W"},{"key":"e_1_2_1_33_2","first-page":"363","article-title":"Cytogenetic studies in preleukemia: Studies before and after transition to acute leukemia in 17 subjects","volume":"1","author":"Pierre RW","year":"1975","journal-title":"Blood Cells"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830010202"},{"key":"e_1_2_1_35_2","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1182\/blood.V54.4.818.818","article-title":"Correlation between prognosis and bone marrow chromosomal patterns in children with acute nonlymphocytic leukemia: Similarities and differences compared to adults","volume":"54","author":"Benedict WF","year":"1979","journal-title":"Blood"},{"key":"e_1_2_1_36_2","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-197911000-00009"},{"key":"e_1_2_1_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197907)44:1<164::AID-CNCR2820440128>3.0.CO;2-9"},{"key":"e_1_2_1_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910170108"},{"key":"e_1_2_1_39_2","volume-title":"The Chromosomes in Human Cancer and Leukemia","author":"Sandberg AA","year":"1980"},{"key":"e_1_2_1_40_2","first-page":"759","article-title":"Nonrandom chromosomal abnormalities in acute nonlymphocytic leukemia in patients treated for Hodgkin's disease and non\u2010Hodgkin's lymphoma","volume":"50","author":"Rowley JD","year":"1977","journal-title":"Blood"},{"key":"e_1_2_1_41_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1975.tb00888.x"},{"key":"e_1_2_1_42_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197903013000902"},{"key":"e_1_2_1_43_2","first-page":"35","article-title":"Second malignancies complicating Hodgkin's disease: The Southwest Oncology Group Experience","volume":"18","author":"Toland DM","year":"1977","journal-title":"Proc Am Soc Clin Oncol"},{"key":"e_1_2_1_44_2","first-page":"25","article-title":"Radiation carcinogenesis","volume":"3","author":"Hirohata T","year":"1976","journal-title":"Semin Oncol"}],"container-title":["Medical and Pediatric Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmpo.2950090110","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mpo.2950090110","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T02:30:08Z","timestamp":1699842608000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mpo.2950090110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,1]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1981,1]]}},"alternative-id":["10.1002\/mpo.2950090110"],"URL":"https:\/\/doi.org\/10.1002\/mpo.2950090110","archive":["Portico"],"relation":{},"ISSN":["0098-1532","1096-911X"],"issn-type":[{"value":"0098-1532","type":"print"},{"value":"1096-911X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,1]]}}}