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This improved survival rate is most likely a result of adjuvant chemotherapy. Forty percent of the patients appear chronically ill, which reflects the fact that nearly 60% have metastases when they are first seen. In localized disease (stages I\u2013II), the prognosis was favourable (cure rate 69%), while the prognosis for disseminated disease (stage III\u2013IV) was poor (cure rate 5%). A favourable outcome was seen in patients under 1 year (survival rate 46%), and in patients with primary tumours located in the neck or mediastinum (survival rate 48%). When related to stage, however, the survival rates for the former tumours were not significantly better in patients below 1 year or in patients with cervical or thoracic tumours. As is the case in other studies, we found that survival is significantly poorer in males.<\/jats:p>","DOI":"10.1002\/mpo.2950130404","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T15:52:16Z","timestamp":1171986736000},"page":"180-186","source":"Crossref","is-referenced-by-count":16,"title":["Neuroblastomas treated at the four major child oncologic clinics in Denmark 1943\u20131980: An evaluation of 180 cases"],"prefix":"10.1002","volume":"13","author":[{"given":"Niels L. 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