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Nosocomial infections occurred in 42% of the patients evaluated. Several risk factors were assessed, and only neutropenia, and previous steroid therapy played a causal role (p &lt; .05) when assessed in a retrospective case control fashion. Overall mortality in oncology patients with LD (53%) was high and underscores the need rapidly to diagnose and treat this entity. This mortality decreased after 1977 when an effective antibiotic was utilized. Mixed infections also played a major role in outcome and occurred in 31% of the 36 patients studied. The mortality in these cancer patients was 73%, and this emphasizes the need to exclude and treat concomitant bacterial or fungal infections.<\/jats:p>","DOI":"10.1002\/mpo.2950140205","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T15:47:43Z","timestamp":1171986463000},"page":"81-85","source":"Crossref","is-referenced-by-count":13,"title":["Legionnaires' disease in patients with cancer"],"prefix":"10.1002","volume":"14","author":[{"given":"Johannes C.","family":"Nunnink","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James G.","family":"Gallagher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerome W.","family":"Yates","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-94-2-164"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(84)90291-2"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.41.1.9-16.1981"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/oxfordjournals.aje.a113756","article-title":"Legionnaires' disease: The epidemiology of two outbreaks in Burlington, Vermont, 1980","volume":"119","author":"Klaucke DN","year":"1980","journal-title":"Am J Epidemiology"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198002143020703"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/5.2.258"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(84)90243-2"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","unstructured":"TobinJD DunnillMS FrenchM et al:Legionnaires' Disease in a transplant unit: Isolation of the causative agent from shower baths. 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