{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T13:11:36Z","timestamp":1698066696897},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,20]],"date-time":"2006-07-20T00:00:00Z","timestamp":1153353600000},"content-version":"vor","delay-in-days":6044,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med. Pediatr. Oncol."],"published-print":{"date-parts":[[1990,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The size of the mediastinal mass on standard posterior\u2010anterior chest radiograph in stage I and stage II Hodgkin's disease has both prognostic and therapeutic importance. But the actual treatment is based on the anterior\u2010posterior supine simulation film. Problems arise when the prognosis (whether all the disease can be effectively contained in an irradiation port) and toxicity (more lung and heart irradiated or chemotherapy required) are changed when the mass is markedly enlarged on the radiation simulation film. We report two patients with small mediastinal masses on standard posterior\u2010anterior chest radiographs that appeared to enlarge markedly on radiation simulation films. Differences in the direction of the X\u2010ray beam, distance from the subject, and patient position are shown to increase artificially the size of a mediastinal mass on simulation films. The staging and therapeutic implications are discussed.<\/jats:p>","DOI":"10.1002\/mpo.2950180109","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T18:10:00Z","timestamp":1171995000000},"page":"44-48","source":"Crossref","is-referenced-by-count":1,"title":["Enlargement of mediastinal masses on simulation films: A radiotherapeutic problem in the management of patients with Hodgkin's disease"],"prefix":"10.1002","volume":"18","author":[{"given":"Svetislava J.","family":"Vukelja","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yvonne","family":"Andejeski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey K.","family":"Giguere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Yuen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis F.","family":"Diehl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000413252"},{"key":"e_1_2_1_3_2","first-page":"809","article-title":"Influence of mediastinal adenopathy on site and frequency of relapse in patients with Hodgkin's disease","volume":"6","author":"Mauch P","year":"1982","journal-title":"Cancer Treat Rep"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V59.3.455.455"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19830701)52:1<8::AID-CNCR2820520103>3.0.CO;2-Z"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197606)37:6<2813::AID-CNCR2820370637>3.0.CO;2-S"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(85)90273-1"},{"key":"e_1_2_1_8_2","first-page":"126","article-title":"Importance of staging in Hodgkin's disease","volume":"7","author":"Jones SE","year":"1980","journal-title":"Semin Oncol"},{"key":"e_1_2_1_9_2","first-page":"2","volume-title":"Update, Cancer: Principles and Practice of Oncology","author":"DeLaney TF","year":"1987"},{"key":"e_1_2_1_10_2","first-page":"767","article-title":"The strategic role of laparotomy in staging Hodgkin's disease","volume":"66","author":"Larson RA","year":"1982","journal-title":"Cancer Treat Rep"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)42086-4"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870915)60:6<1232::AID-CNCR2820600612>3.0.CO;2-F"}],"container-title":["Medical and Pediatric Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmpo.2950180109","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mpo.2950180109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T19:30:37Z","timestamp":1698003037000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mpo.2950180109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1990,1]]}},"alternative-id":["10.1002\/mpo.2950180109"],"URL":"https:\/\/doi.org\/10.1002\/mpo.2950180109","archive":["Portico"],"relation":{},"ISSN":["0098-1532","1096-911X"],"issn-type":[{"value":"0098-1532","type":"print"},{"value":"1096-911X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,1]]}}}