{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:20:01Z","timestamp":1779358801335,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,7,20]],"date-time":"2006-07-20T00:00:00Z","timestamp":1153353600000},"content-version":"vor","delay-in-days":6044,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med. Pediatr. Oncol."],"published-print":{"date-parts":[[1990,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Twenty\u2010four children with superior vena cava obstruction at initial presentation or associated with disease recurrence were treated at St. Jude Children's Research Hospital from 1973 to 1988. Of the 16 patients with superior vena cava syndrome at presentation, eight had non\u2010Hodgkin's lymphoma, four had acute lymphoblastic leukemia, two had Hodgkin's disease, one had neuroblastoma, and one had a yolk sac tumor. Their clinical condition at presentation was often critical and required rapid treatment. In all cases, histopathologic diagnosis was obtained without complication by either bone marrow aspiration, lymph node biopsy, thoracentesis, or thoracotomy prior to the initiation of definitive therapy.<\/jats:p><jats:p>Eight children had superior vena cava syndrome as a late complication during the course of their therapy. None had an antecedent history of superior vena cava obstruction. In contrast to the patients with superior vena cava obstruction at presentation, this group was composed predominantly of patients with recurrent solid tumors. Other causes included disseminated candidiasis and superior vena cava thrombosis, thus underscoring the importance of recognizing the etiology of superior vena cava syndrome to facilitate proper treatment.<\/jats:p>","DOI":"10.1002\/mpo.2950180608","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T18:06:04Z","timestamp":1171994764000},"page":"476-481","source":"Crossref","is-referenced-by-count":60,"title":["Superior vena cava syndrome associated with childhood malignancy: Analysis of 24 cases"],"prefix":"10.1002","volume":"18","author":[{"given":"Lewis","family":"Ingram","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaston K.","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David N.","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"323","article-title":"The history of an aneurysm of the aorta with some variants on aneurysms in general","volume":"1","author":"Hunter W","year":"1757","journal-title":"Med Obs Soc Phys (Lond)"},{"key":"e_1_2_1_3_2","first-page":"537","article-title":"The superior mediastinal syndrome in children with cancer","volume":"95","author":"D'Angio GD","year":"1965","journal-title":"Am J Roentgenol Radium Ther Nucl Med"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0147-0272(86)80006-X"},{"key":"e_1_2_1_5_2","first-page":"799","volume-title":"Principles and Practice of Pediatric Oncology","author":"Lange B","year":"1989"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1200\/JCO.1984.2.4.260","article-title":"Clinical features and results of management of superior vena cava syndrome secondary to lymphoma","volume":"2","author":"Perez\u2010Soler R","year":"1984","journal-title":"J Clin Oncol"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1200\/JCO.1984.2.8.961","article-title":"A reassessment of the clinical implications of the superior vena cava syndrome","volume":"2","author":"Ahmann FR","year":"1984","journal-title":"J Clin Oncol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1542\/peds.71.3.337","article-title":"Superior vena cava syndrome in childhood: Report of ten cases and review of the literature","volume":"71","author":"Issa PY","year":"1983","journal-title":"Pediatrics"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.143.4.731"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80908-6"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/71.1.10"},{"key":"e_1_2_1_12_2","first-page":"1971","volume-title":"Cancer: Principals and Practice","author":"Yahalon J","year":"1989"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80535-0"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(82)80015-8"},{"key":"e_1_2_1_15_2","first-page":"407","article-title":"Etiologic considerations in superior vena cava syndrome","volume":"56","author":"Parish JM","year":"1981","journal-title":"Mayo Clin Proc"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.139.6.1167"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(56)80016-4"},{"key":"e_1_2_1_18_2","first-page":"561","article-title":"Malignant teratoma of the heart: Report of a case with necropsy","volume":"52","author":"Solomon RD","year":"1951","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/000992287101001030"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950070305"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80948-8"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196505000-00016"},{"key":"e_1_2_1_23_2","first-page":"52","article-title":"Superior vena cava syndrome","volume":"213","author":"Lokkich JJ","year":"1975","journal-title":"JAMA"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198402000-00012"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197812)42:6<2600::AID-CNCR2820420614>3.0.CO;2-2"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1986.4.5.716"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197208242870806"}],"container-title":["Medical and Pediatric Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmpo.2950180608","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mpo.2950180608","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T19:17:48Z","timestamp":1698002268000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mpo.2950180608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,1]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1990,1]]}},"alternative-id":["10.1002\/mpo.2950180608"],"URL":"https:\/\/doi.org\/10.1002\/mpo.2950180608","archive":["Portico"],"relation":{},"ISSN":["0098-1532","1096-911X"],"issn-type":[{"value":"0098-1532","type":"print"},{"value":"1096-911X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,1]]}}}