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In the absence of other causes it seems probable that high dose cisplatin (200 mg\/m<jats:sup>2<\/jats:sup>) as a continuous infusion over five days followed 10 days later by 80 mg\/m<jats:sup>2<\/jats:sup> infused over 48 hours was responsible. Other risk factors included an associated deterioration in renal function and neutropenia related fever.<\/jats:p>","DOI":"10.1002\/mpo.2950200210","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T18:21:47Z","timestamp":1171995707000},"page":"143-148","source":"Crossref","is-referenced-by-count":32,"title":["Seizures and cortical dysfunction following high\u2010dose cisplatin administration in children"],"prefix":"10.1002","volume":"20","author":[{"given":"Martin","family":"Highley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon T.","family":"Meller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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