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Complete immunopheno\u2010typing was performed in 206 cases (82%). Out of these 175 cases were classified as B\u2010cell precursor ALL, 31 cases as T\u2010ALL. Expression of myeloid\u2010associated antigens was demonstrated in 23 cases (13.1%) of childhood B\u2010cell precursor ALL, particularly in immature (CD10 negative) forms (<jats:italic>P<\/jats:italic>&lt; .0001), and in 1 case (3.2%) of T\u2010ALL. CDw65 was expressed most frequently (12 cases), followed by CD13 and CD15 (5 cases each), CD33 (4 cases), and blood\u2010group H (3 cases). Compared to myA\u2010 ALL prognosis of children with myA+ B\u2010cell precursor ALL was poor, despite intensive multiagent chemotherapy according to BFM protocols. Remission rates were not impaired, but pEFS was 74.6% for myA\u2010 ALL, and only 37.8% for myA+ ALL (<jats:italic>P<\/jats:italic>= .0001). As demonstrated by multivariate analysis the expression of myeloid\u2010associated antigens was the most important prognostic variable for EFS in B\u2010cell precursor ALL, whether or not CD10 was expressed. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mpo.2950210506","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T18:59:39Z","timestamp":1171997979000},"page":"340-346","source":"Crossref","is-referenced-by-count":25,"title":["Prognostic significance of myeloid\u2010associated antigen expression on blast cells in children with acute lymphoblastic leukemia"],"prefix":"10.1002","volume":"21","author":[{"given":"Franz\u2010Martin","family":"Fink","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"K\u00f6ller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannes","family":"Mayer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oskar A.","family":"Haas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. 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