{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:14:59Z","timestamp":1770822899697,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2006,7,20]],"date-time":"2006-07-20T00:00:00Z","timestamp":1153353600000},"content-version":"vor","delay-in-days":4948,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med. Pediatr. Oncol."],"published-print":{"date-parts":[[1993,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Carcinoma of the choroid plexus (CCP) is a rare tumor of the central nervous system which occurs more frequently in patients under 3 years of age. We report 10 cases of CCP in children. There were 5 males and 5 females, aged 5 to 84 months at diagnosis (median 32 months). Eight CCP were located in the lateral ventricle and 2 in the fourth ventricle. All patients underwent initial surgery, with complete resection in 5 cases. Postoperative treatment included radiotherapy alone in 4 patients, chemotherapy alone in 4, both in 1 patient, and no further treatment in one patient. Six patients remain in first continuous complete remission with a follow\u2010up of 12 to 156 months (mean 34 months). Five of these six patients had a complete surgical resection of their tumor and 4 of them received chemotherapy alone. A comparison with the series in the literature suggests that total resection of the tumors is the major prognostic factor for survival. Recourse to additional treatments to prevent local relapses and CNS dissemination seems necessary. In our opinion, radiotherapy should be avoided as far as possible because of its deleterious effect in very young children. As some of the long term survivors did not receive radiation treatment, we conclude that CCP can be treated post operatively using chemotherapy protocols designed for infants with malignant brain tumors. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mpo.2950210705","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T18:57:38Z","timestamp":1171997858000},"page":"480-487","source":"Crossref","is-referenced-by-count":55,"title":["Carcinoma of the choroid plexus: A pediatric experience"],"prefix":"10.1002","volume":"21","author":[{"given":"Jean\u2010Yves","family":"Pierga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chantal","family":"Kalifa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie\u2010Jose","family":"Terrier\u2010Lacombe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Louts","family":"Habrand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Lemerle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"issue":"3","key":"e_1_2_1_2_2","first-page":"461","article-title":"Choroid plexus carcinoma: Responses to chemotherapy alone in newly diagnosed young children","volume":"26","author":"Allen JC","year":"1989","journal-title":"Ann Neurol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900615)65:12<2712::AID-CNCR2820651219>3.0.CO;2-H"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1983.tb02308.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-3019(84)90305-7"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-44-522-412"},{"key":"e_1_2_1_7_2","first-page":"213","article-title":"Eight drugs in one day chemotherapy for brain tumors: A new approach and rational for pre\u2010Irradiation chemotherapy","volume":"11","author":"Bleyer WA","year":"1983","journal-title":"Med Pediatr Oncol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-197903000-00008"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1961.18.4.0493"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1987.66.6.0800"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1017\/S0317167100046011","article-title":"Third ventricle choroid plexus carcinoma","volume":"11","author":"Broad RW","year":"1984","journal-title":"Can J Neurol Sci"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1982.56.5.0722"},{"key":"e_1_2_1_13_2","first-page":"239","article-title":"Choroid plexus carcinoma. 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