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Both groups received four\u2010drug induction chemotherapy, which produced a high remission rate. Those receiving DNR on days 1 and 2 experienced a profound but shorter period of neutropenia and more severe thrombocytopenia than those who received the DNR weekly. The pattern of hospitalisation and support facilities in the individual unit may determine which regimen is to be preferred. These observations are relevant for the newly diagnosed patient in whom an anthracycline is retained in the induction therapy for ALL. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mpo.2950240105","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T19:26:10Z","timestamp":1171999570000},"page":"18-22","source":"Crossref","is-referenced-by-count":6,"title":["Induction toxicity in childhood acute lymphoblastic leukemia: A comparison of two schedules of daunorubicin administration"],"prefix":"10.1002","volume":"24","author":[{"given":"Peter J.","family":"Shaw","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Eden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Paradisis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950140405"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1991.tb04415.x"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-84722-6_9"},{"key":"e_1_2_1_5_2","first-page":"157","article-title":"MRC UKALL X. 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