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In children, the tumors most often associated with the development of SMN are retinoblastoma and Hodgkin's disease.<\/jats:p><jats:p>We report two cases of unusual second tumors in two patients cured of lymphoid malignancy: one boy cured of acute lymphoblastic leukemia developed mediastinal ganglioneuroma nine years later and one girl had gastric carcinoma seven years after Hodgkin's disease. Both developed a tumor in nonirradiated areas.<\/jats:p><jats:p>Gastric carcinoma and ganglioneuroma are not reported as recurrent SMN in survivors after childhood cancer, with one single case of gastric carcinoma and one of ganglioneuroblastoma having been reported as second tumor in survivors after childhood cancer. \u00a9 1995 Wi1ey\u2010Liss Inc.<\/jats:p>","DOI":"10.1002\/mpo.2950240310","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T19:24:34Z","timestamp":1171999474000},"page":"197-199","source":"Crossref","is-referenced-by-count":6,"title":["Unusual secondary tumors after childhood lymphoid malignancy"],"prefix":"10.1002","volume":"24","author":[{"given":"Maurizio","family":"Aric\u00f2","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grazia","family":"Bossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Cecchetto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrizia","family":"Dall'Igna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Vigan\u00f2","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860715)58:2 <598::AID-CNCR2820581332>3.0.CO;2-C"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197808)42:2 <1015::AID-CNCR2820420725>3.0.CO;2-G"},{"key":"e_1_2_1_4_2","first-page":"263","volume-title":"Status of the Curability of Childhood Cancers","author":"Meadows AT","year":"1980"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199111073251902"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198912283212612"},{"key":"e_1_2_1_7_2","first-page":"211","volume-title":"Radiation Carcinogenesis: Epidemiology and Biological Significance","author":"Tucker MA","year":"1984"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860601)57:11<2250::AID-CNCR2820571131>3.0.CO;2-H"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860301)57:5<1052::AID-CNCR2820570530>3.0.CO;2-0"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0277-5379(87)90309-9"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1987.200"},{"key":"e_1_2_1_12_2","first-page":"125","article-title":"Risk factors for second malignant neoplasms: Report from the Late Effects Study Group","volume":"75","author":"Meadows AT","year":"1988","journal-title":"Bull Cancer"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950170525"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1989.165"},{"key":"e_1_2_1_15_2","unstructured":"PrattGB HancockML ParhamD KunLE ThompsonEI MirroJ PuiCH CristWM GeorgeSL: Second malignant neoplasms developing after treatment of childhood solid tumors.Med Pediatr Oncol(in press)."},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(93)90533-L"},{"key":"e_1_2_1_17_2","unstructured":"EpelmanSE GorenderEF AnelliA SteinbergS BianchiA:The risk of second malignant neoplasms (SMN) following childhood cancer. Results of a single institution. 2nd International Conference on Long\u2010Term Complications of Treatment of Children and Adolescents for Cancer. June 12\u201314 1992. Buffalo New York. Abs n. 21."},{"key":"e_1_2_1_18_2","unstructured":"GreenD ZevonM ReeseP LowrieG MichalekA GaetaJ:Second malignant tumors following treatment for cancer in childhood and adolescence. 2nd International Conference on Long\u2010Term Complications of Treatment of Children and Adolescents for Cancer. June 12\u201314 1992. Buffalo New York Abs n. 26."},{"key":"e_1_2_1_19_2","unstructured":"CristofaniLM FurrerA CornacchionniAL PassoniR AlmeidaMT BritoJL LogettoS MalufPT Odone\u2010FilhoV:2nd International Conference on Long\u2010Term Complications of Treatment of Children and Adolescents for Cancer. June 12\u201314 1992. Buffalo New York. 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