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Platelet aggregations with thrombin and collagen and the number of major platelet glycoproteins\/per platelet did not differ from the controls. After Haemate P\u00ae (Behring Werke, Marburg, Germany) bleeding time normalized and surgery could be performed without occurrence of bleeding episodes. Three weeks after surgery bleeding time, ristocetin cofactor activity, and von Willebrand factor antigen increased to normal paediatric values. 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