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This investigational compound was employed in a 50\u2010year\u2010old patient with acute myelomonocytic leukemia complicated by prolonged, treatment\u2010induced granulocytopenia and documented <jats:italic>Aspergillus flavus<\/jats:italic> sinusitis with signs of disseminated aspergillosis. The patient demonstrated radiographic signs of pulmonary aspergillosis and biochemical signs of hepatic involvement that were resistant to a 23 day course of conventional AMB (Fungizone\u00ae) therapy. Following therapy with ABLC\u2122 her fever abated, her chest X\u2010ray findings improved, and her hepatic function tests improved with eventual resolution. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mpo.2950250214","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T19:22:21Z","timestamp":1171999341000},"page":"119-122","source":"Crossref","is-referenced-by-count":18,"title":["Successful treatment of invasive aspergillosis complicating prolonged treatment\u2010related neutropenia in acute myelogenous leukemia with amphotericin B lipid complex"],"prefix":"10.1002","volume":"25","author":[{"given":"Duane R.","family":"Hospenthal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Byrd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond B.","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1200\/JCO.1987.5.12.1985","article-title":"Favorable outcome of invasive aspergillosis in patients with acute leukemia","volume":"5","author":"Burch PA","year":"1987","journal-title":"J Clin Oncol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/12.6.1147"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(90)70263-H"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/17.Supplement_2.S501"},{"key":"e_1_2_1_6_2","first-page":"138","article-title":"Fludarabine therapy for lymphoid malignancies is associated with a high incidence of opportunistic pulmonary infections","volume":"82","author":"Byrd JC","year":"1993","journal-title":"Blood"},{"key":"e_1_2_1_7_2","first-page":"199","article-title":"Fludarabine versus cyclophosphamide, adriamycin, prednisone (CAP) for the treatment of chronic lymphocytic leukemia: Results of a multinational prospective randomized trial","volume":"82","author":"Hiddeman W","year":"1993","journal-title":"Blood"},{"key":"e_1_2_1_8_2","first-page":"201","volume-title":"Medical Mycology","author":"Kwon\u2010Chung KJ","year":"1992"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/13.3.496"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90184-Y"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.35.4.615"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.35.10.2144"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/02681219280000491"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/164.2.418"},{"key":"e_1_2_1_15_2","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1542\/peds.93.5.830","article-title":"Successful medical therapy of Aspergillus osteomyelitis of the spine in an 11\u2010year\u2010old boy with chronic granulomatous disease","volume":"93","author":"Kline MW","year":"1994","journal-title":"Pediatrics"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1987.5.2.310"},{"key":"e_1_2_1_17_2","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1001\/archinte.1989.00390110097022","article-title":"Treatment of systemic fungal infection with liposomal amphotericin B","volume":"149","author":"Lopez\u2010Berestein G","year":"1989","journal-title":"Arch Intern Med"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/151.4.704"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1994.12.4.671"}],"container-title":["Medical and Pediatric Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmpo.2950250214","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mpo.2950250214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T00:51:06Z","timestamp":1698281466000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mpo.2950250214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,8]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1995,8]]}},"alternative-id":["10.1002\/mpo.2950250214"],"URL":"https:\/\/doi.org\/10.1002\/mpo.2950250214","archive":["Portico"],"relation":{},"ISSN":["0098-1532","1096-911X"],"issn-type":[{"value":"0098-1532","type":"print"},{"value":"1096-911X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,8]]}}}