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Experimental studies comparing underlying mechanisms of addictions and analyzing data from an integrative psychological and genetic perspective are almost nonexistent. The aim of the present paper is to describe the research protocol of the Psychological and Genetic Factors of Addictive Behaviors (PGA) study, which applies an integrative approach to understanding the acquisition, development, and maintenance of addictive behaviors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A wide\u2010spectrum national study was carried out. Data were collected from 3,003 adolescents. Addictions to both psychoactive substances and behaviors were thoroughly assessed via psychometrically robust scales, which also included assessment related to a wide range of related psychological dimensions. Additionally, a DNA sample was also collected from participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The paper presents the detailed methodology of the PGA study. Data collection procedures, instrumentation, and the analytical approach used to attain the research objectives are described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Future plans, along with potential contributions of the PGA study, are also discussed. It is envisaged that the study will provide a unique opportunity to test possible mechanisms and causal pathways mediating the associations of genetic factors, psychological characteristics, and addictions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mpr.1748","type":"journal-article","created":{"date-parts":[[2018,11,7]],"date-time":"2018-11-07T06:34:50Z","timestamp":1541572490000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The psychological and genetic factors of the addictive behaviors (PGA) study"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6630-087X","authenticated-orcid":false,"given":"Eszter","family":"Kotyuk","sequence":"first","affiliation":[{"name":"Department of Clinical Psychology and Addiction, Institute of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"},{"name":"Postdoctoral Research Program Hungarian Academy of Sciences  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit","family":"Farkas","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Addiction, Institute of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Magi","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Addiction, Institute of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"},{"name":"Doctoral School of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Eisinger","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Addiction, Institute of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"},{"name":"Doctoral School of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orsolya","family":"Kir\u00e1ly","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Addiction, Institute of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Vereczkei","sequence":"additional","affiliation":[{"name":"Department of Medical Chemistry, Molecular Biology and Pathobiochemistry Semmelweis University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Csaba","family":"Barta","sequence":"additional","affiliation":[{"name":"Department of Medical Chemistry, Molecular Biology and Pathobiochemistry Semmelweis University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark D.","family":"Griffiths","sequence":"additional","affiliation":[{"name":"International Gaming Research Unit, Psychology Department Nottingham Trent University  Nottingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6ngyi","family":"K\u00f6k\u00f6nyei","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Addiction, Institute of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Sz\u00e9kely","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Addiction, Institute of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1ria","family":"Sasv\u00e1ri\u2010Sz\u00e9kely","sequence":"additional","affiliation":[{"name":"Department of Medical Chemistry, Molecular Biology and Pathobiochemistry Semmelweis University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5604-7551","authenticated-orcid":false,"given":"Zsolt","family":"Demetrovics","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Addiction, Institute of Psychology ELTE E\u00f6tv\u00f6s Lor\u00e1nd University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2008.02213.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.54"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2466\/02.09.18.PR0.110.2.501-517"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169839"},{"volume-title":"The addiction\u2010prone personality","year":"2000","author":"Barnes G. 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