{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T05:59:14Z","timestamp":1764655154129,"version":"3.46.0"},"reference-count":76,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006364","name":"Institut National Du Cancer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006364","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020320","name":"Institut pour la Recherche en Sant\u00e9 Publique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020320","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Methods Psych Res"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The purpose of this paper is to describe a study protocol of a clinical trial exploring the effectiveness of the new mobile application MyD\u00e9fi proposing personalized feedback, on both alcohol consumption and quality of life, as well as the blood alcohol exposure biomarker phosphatidylethanol, in university students displaying binge drinking behavior.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective national multicentric randomized, two\u2010arm (1:1), double\u2010blind controlled trial will recruit 628 students (aged 18\u201325\u00a0years) with binge drinking behavior. Participants will be randomized in the \u201cintervention\u201d group (personalized feedback) or the \u201ccontrol\u201d group (generic feedback) and will undergo four monthly visits. Monthly dried blood spot sample for measuring phosphatidylethanol concentration and online questionnaires will be collected. Our primary objective is to assess the reduction weekly standard drinks, through self\u2010report gathered via MyD\u00e9fi. Secondary objectives will evaluate the application's impact on the dosage of phosphatidylethanol blood concentration and on quality of life\u201d.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Recruitment started in March 2024 and will end in March 2026.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study aims to determine the effectiveness of two versions of the same mobile application (generic vs. personalized feedback) on alcohol consumption in students displaying binge drinking behavior. The effectiveness of the application will be measured, with a secondary objective of quantifying phosphatidylethanol. Our study will open new perspectives on the use of digital interventions for students who do not actively seek treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      Trial registration number (NCT06084832), the date of registration (10th October 2023) and when this was done (16th October 2023).\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/clinicaltrials.gov\/study\/NCT06084832\">https:\/\/clinicaltrials.gov\/study\/NCT06084832<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mpr.70014","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T23:56:29Z","timestamp":1743551789000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of the MyD\u00e9fi Smartphone Application on Binge Drinking\u00a0Among University Students: Protocol of a Double\u2010Blind Multicenter Prospective National Randomized Controlled Trial Using Phosphatidylethanol as a Biomarker\u2014The SMARTBINGE Trial"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6346-6809","authenticated-orcid":false,"given":"Camille","family":"Andr\u00e9","sequence":"first","affiliation":[{"name":"Groupe de Recherche sur l\u2019Alcool &amp; 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