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We evaluated reliability, construct validity, convergent and discriminant validity, and diagnostic accuracy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Regarding reliability, the instrument demonstrated robust internal consistency, supported by strong Cronbach's alpha and McDonald's omega coefficients. In terms of construct validity, Exploratory Factor Analysis (EFA) indicated a single\u2010factor solution, while the H\u2010index supported a replicable latent structure. However, formal assessments of closeness to unidimensionality suggested that the scale is not strictly unidimensional. For convergent and discriminant validity, correlational analyses showed a moderate association with anxiety symptoms and weak associations with substance use measures, respectively. Regarding accuracy, ROC curve analysis indicated that a cutoff score of 9 is useful for screening, whereas 18 may better identify a depressive episode.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>While the MADRS remains a valuable tool, structural refinements could further enhance its psychometric performance across distinct clinical settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mpr.70113","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T04:01:33Z","timestamp":1791777693000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["New Insights About the Psychometric Properties of the Montgomery\u2010Asberg Depression Rating Scale"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4016-0473","authenticated-orcid":false,"given":"Samuel Vieira Pinho","family":"Neto","sequence":"first","affiliation":[{"name":"Psychiatry Residency Program Mental Health Hospital Professor Frota Pinto  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0500-1929","authenticated-orcid":false,"given":"Erivan de Olivindo","family":"Cavalcante","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Federal University of Cear\u00e1  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8133-629X","authenticated-orcid":false,"given":"Mariana Alves","family":"Le\u00e3o","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Federal University of Cear\u00e1  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4902-5669","authenticated-orcid":false,"given":"Alexandre Menezes","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Center for Health Sciences University of Fortaleza  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3195-6852","authenticated-orcid":false,"given":"Matias Carvalho Aguiar","family":"Melo","sequence":"additional","affiliation":[{"name":"Center for Health Sciences University of Fortaleza  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9034-981X","authenticated-orcid":false,"given":"Paulo Rodrigues Nunes","family":"Neto","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Federal University of Cear\u00e1  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,11]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2013.03.001"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1516\u201044462000000300003"},{"key":"e_1_2_13_5_1","article-title":"Tests of Significance in Factor Analysis","author":"Bartlett M. 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